132125-61-2

Basic information

• Product Name: ((1R,2R)-1,2-Dihydroxy-propyl)-phosphonic acid; compound with cyclohexylamine
• CAS NO: 132125-61-2
• Molecular Weight: 609.678
• Mol File: 132125-61-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ((1R,2R)-1,2-Dihydroxy-propyl)-phosphonic acid; compound with cyclohexylamine(CAS DataBase Reference)
• NIST Chemistry Reference: ((1R,2R)-1,2-Dihydroxy-propyl)-phosphonic acid; compound with cyclohexylamine(132125-61-2)
• EPA Substance Registry System: ((1R,2R)-1,2-Dihydroxy-propyl)-phosphonic acid; compound with cyclohexylamine(132125-61-2)

Safety Data

• Hazardous Substances Data: 132125-61-2(Hazardous Substances Data)

Upstream product

• 26016-99-9 phosphomycin disodium salt 
• 108-91-8 cyclohexylamine 

Relevant articles and documents

Addition of Dialkyl Phosphites and Dialkyl Trimethylsilyl Phosphites to 2-(Benzyloxy)propanal - Preparation of all Four Stereoisomeric (1,2-Dihydroxy-2H1>propyl)phosphonic Acids from Chiral Lactates

Dimethyl trimethylsilyl phosphite, diisopropyl trimethylsilyl phosphite, dimethyl phosphite, and diisopropyl phosphite were added to 2-(benzyloxy)propanals 4 and 6 at different temperatures in THF and CH2Cl2.The ratio of diastereomers formed was highest for diisopropyl trimethylsilyl phosphite (erythro/threo 3:1) and dropped to about 1:1 for diisopropy phosphite.Starting from chiral lactates all four stereoisomeric diisopropyl (2-benzyloxy-1-hydroxy-2H1>phosphonates were prepared and deprotected.The (1,2-dihydroxy-2H1>propyl)phosphonic acids formed were purified as cyclohexylammonium salts.The relative configuration of phosph onic acid of (-)-11 was determined by comparison with the salt (1R,2R)-12 derived from fosfomycin.