132185-84-3

Basic information

• Product Name: 5beta-Hydroxycostic acid
• Synonyms: 5beta-Hydroxycostic acid;(2R,4aR,8aS)-Decahydro-8a-hydroxy-4a-methyl-alpha,8-bis(methylene)-2-naphthaleneacetic acid
• CAS NO: 132185-84-3
• Molecular Formula: C15H22O3
• Molecular Weight: 250.33338
• Mol File: 132185-84-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 406.4±38.0 °C(Predicted)
• Appearance: /
• Density: 1.12±0.1 g/cm3(Predicted)
• PKA: 4.42±0.11(Predicted)
• CAS DataBase Reference: 5beta-Hydroxycostic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5beta-Hydroxycostic acid(132185-84-3)
• EPA Substance Registry System: 5beta-Hydroxycostic acid(132185-84-3)

Safety Data

• Hazardous Substances Data: 132185-84-3(Hazardous Substances Data)

Usage

Uses

(2R,4aR,8aS)-Decahydro-8a-hydroxy-4a-methyl-α,8-bis(methylene)-2-naphthaleneacetic acid is extracted from the roots of Saussurea lappa, and Laggera pterodonta, may have anti-viral properties and used in traditional chinese medicine.

Relevant articles and documents

Eudesmane and megastigmane glucosides from Laggera alata

Four eudesmane glucosides, alatosides A-D (1-4), and one megastigmane glucoside, alatoside E (5), were isolated from the BuOH fraction of Laggera alata along with six known compounds. Structures of the new compounds were elucidated by a combination of chemical and spectroscopic methods. Alatosides A-E were characterized as: 1α-O-(β-D-glucopyranosyloxyl)-7-epi-eudesma-11-en-2β, 4α-diol (1), 2β-O-(β-D-glucopyranosyloxyl)-eudesma-4α-hydroxyl-11(13)- en-12-oic-acid (2), 5β-O-β-D-glucopyranosyloxyl)-eudesma-4(15), 11(13)-dien-12-oic-acid (3), 5α-O-(β-D-glucopyranosyloxyl)-eudesma-3,11 (13)-dien-12-oic acid (4) and 3β-O-(β-D-glucopyranosyloxyl)-megastigma-9-one (5), respectively. Based on the chemical characteristics of eudesmane derivatives isolated from the Laggera genus, it was suggested that there are probably two different biogenetic pathways for these secondary metabolites in this genus.