132206-92-9Relevant articles and documents
A3 ADENOSINE RECEPTOR ALLOSTERIC MODULATORS
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Page/Page column 25-26, (2008/06/13)
The present invention relates to allosteric modulation of A3 adenosine receptor (A3AR) and provides for the use of an A3 adenosine receptor modulator (A3RM),for the preparation of pharmaceutical compositions for
1H-imidazo?4,5-c!quinolin-4-amines
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, (2008/06/13)
Novel 1H-imidazo?4,5-c!quinolin-4-amines are disclosed. The compounds function as antiviral agents and they are potential synthetic intermediates in the preparation of known antiviral agents and labeled known antiviral agents. Processes for the preparation of the compounds, methods for their antiviral use, and methods of inducing interferon biosynthesis, are also described.
1H-Imidazoquinolin-4-amines: Novel Non-Xanthine Adenosine Antagonists
Galen, Philip J. M. van,Nissen, Peter,Wijngaarden, Ineke van,IJzerman, Adriaan P.,Soudijn, Willem
, p. 1202 - 1206 (2007/10/02)
On the basis of a model we recently developed for the antagonist binding site of the adenosine A1 receptor (J.Med.Chem. 1990, 33, 1708-1713), it was predicted that 1H-imidazoquinolin-4-amines would be antagonists of the A1 rec