132244-31-6

Basic information

• Product Name: 5-BROMO-BENZOOXAZOLE
• Synonyms: 5-BROMO-BENZOOXAZOLE;5-BROMOBENZOXAZOLE;CHEMBRDG-BB 4002139;5-BROMO-1,3-BENZOXAZOLE;5-BROMOBENZO[D]OXAZOLE;5-BROMOBENZO[D]OXAZOLE ,97%;5-bromo-1,3-benzoxazole(SALTDATA: FREE);Benzoxazole, 5-broMo-
• CAS NO: 132244-31-6
• Molecular Formula: C₇H₄BrNO
• Molecular Weight: 198.01676
• Product Categories: Miscellaneous
• Mol File: 132244-31-6.mol
• Article Data: 16

Chemical Properties

• Melting Point: 38-40°
• Boiling Point: 251.169 °C at 760 mmHg
• Flash Point: 105.704 °C
• Appearance: /
• Density: 1.711g/cm³
• Vapor Pressure: 0.033mmHg at 25°C
• Refractive Index: 1.649
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: -0.85±0.10(Predicted)
• CAS DataBase Reference: 5-BROMO-BENZOOXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-BENZOOXAZOLE(132244-31-6)
• EPA Substance Registry System: 5-BROMO-BENZOOXAZOLE(132244-31-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 132244-31-6(Hazardous Substances Data)

Usage

General Description

5-Bromo-Benzooxazole is a chemical compound that belongs to the organohalogen compound class and specifically to the benzoxazoles subclass. It is characterized by a benzoxazole core structure with a bromine atom attached. The systematic name for this compound is 5-bromo-1,3-benzoxazole. It appears as an off-white to light yellow crystalline solid with a molecular weight of about 198.02 g/mol. 5-Bromo-Benzooxazole is often used in chemical and pharmaceutical research as a raw material or reagent, demonstrating potential utility in the synthesis of a variety of chemical compounds. The chemical stability, reactivity, and potential hazards of 5-Bromo-Benzooxazole, like many chemicals, will vary based on the specific conditions and environments of use.

InChI:InChI=1/C7H4BrNO/c8-5-1-2-7-6(3-5)9-4-10-7/h1-4H

Upstream product

• 40925-68-6 2-amino-4-bromo-phenol 
• 149-73-5 trimethyl orthoformate 
• 124-38-9 carbon dioxide 
• 106-41-2 4-bromo-phenol 
• 7693-52-9 4-bromo-2-nitrophenol 
• 95-56-7 2-hydroxybromobenzene 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 954239-61-3 5-bromo-benzoxazole-2-carboxylic acid methyl ester 
• 944898-52-6 5-bromo-1,3-benzoxazole-2-carboxylic acid 
• 1638125-49-1 (5-bromobenzo[d]oxazol-2-yl)(phenyl)methanone 
• 69918-19-0 5-bromo-2-phenylbenzo[d]oxazole 
• 945531-29-3 5-bromo-2-(p-tolyl)benzo[d]oxazole 
• 2123491-32-5 (S)-(-)-5-(1-(1-(4-fluorophenyl)ethyl)-1H-[1,2,3]-triazolo-[4,5-c]quinolin-8-yl)benzo[d]oxazole 

Relevant articles and documents

Benzoxazoles as Selective Monoamine Oxidase B (MAO-B) Inhibitors

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1,8-NAPHTHYRIDINONE COMPOUNDS AND USES THEREOF

1,8-naphthyridinone compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.

Room-temperature palladium-catalyzed direct 2-alkenylation of azole derivatives with alkenyl bromides

Pd-catalyzed direct C2-alkenylation of azole derivatives proceeds efficiently under mild conditions, and the reaction of substituted benzoxazoles, oxazole and benzothiazole occurred even at room temperature. The substrate scope of the reaction was turned out to include mono-, di- and trisubstituted alkenyl bromides. To validate the scalability of this method, 5-Methyl-2-(prop-1-en-2-yl)benzoxazole (3c) was prepared on one-gram scale at room temperature.