132278-01-4

Basic information

• Product Name: 2-Pentenoyl chloride, 4,4-dimethyl-, (2E)-
• CAS NO: 132278-01-4
• Molecular Formula: C7H11ClO
• Molecular Weight: 146.617
• Mol File: 132278-01-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Pentenoyl chloride, 4,4-dimethyl-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pentenoyl chloride, 4,4-dimethyl-, (2E)-(132278-01-4)
• EPA Substance Registry System: 2-Pentenoyl chloride, 4,4-dimethyl-, (2E)-(132278-01-4)

Safety Data

• Hazardous Substances Data: 132278-01-4(Hazardous Substances Data)

Upstream product

• 16666-45-8 (E)-4,4-dimethyl-2-pentenoic acid 
• 26148-38-9 N¹-(pyridin-2-yl)benzene-1,2-diamine 

Downstream Products

• 678991-35-0 E-(+)-(1'S,2'S)-N-methyl-N-(2'-phenyl-2'-hydroxy-1'-methylethyl)-4,4-dimethylpent-2-enamide 
• 81530-28-1 7-t-butyl-5-oxo-2,3,6,7-tetrahydro-5H-thiazolo-[3,2-a]pyrimidine 
• 678991-40-7 (+)-(1'S,2'S,3S)-3-dibenzylamino-N,4,4-trimethyl-N-(2'-phenyl-2'-hydroxy-1'-methylethyl)pentanamide 
• 869468-27-9 (+)-(1'S,2'S,3S)-3-(benzyloxycarbonyl)amino-N-methyl-N-(2'-phenyl-2'-hydroxy-1'-methylethyl)-4,4-dimethylpentanamide 
• 869468-31-5 (-)-(3S)-3-((benzyloxycarbonyl)amino)-4,4-dimethylpentanol 

Relevant articles and documents

Benzimidazole cyclooxygenase-2 inhibitors

This invention provides a compound of the following formula: or the pharmaceutically acceptable salts thereof, wherein Ar is heteroaryl; X1and X2are independently selected from halo, C1-C4alkyl, hydroxy, C1-C4alkoxy, amino, C1-C4alkanoyl, carboxy, carbamoyl, cyano, nitro, mercapto, (C1-C4alkyl)thio, (C1-C4alkyl)sulfinyl, (C1-C4alkyl)sulfonyl, aminosulfonyl, or the like; R1is selected from hydrogen, straight or branched C1-C4alkyl, C3-C8cycloalkyl, C4-C8cycloalkenyl, phenyl , heteroaryl and the like; R2and R3are independently selected from hydrogen, halo, C1-C4alkyl, phenyl and the like; or R1and R2can form, together with the carbon atom to which they are attached, a C5-C7cycloalkyl ring; and m and n are independently 0, 1, 2 or 3. These compounds and pharmaceutical compositions containing such compounds are useful as analgesics and anti-inflammatory agents.