132454-31-0Relevant articles and documents
Synthese et etude physicochimique des 1,2,4-triazolopyridines et des 1,2,4-triazolopyridines
Bouteau, Brigitte,Lancelot, Jean-Charles,Robba, Max
, p. 1649 - 1651 (2007/10/02)
The synthesis of 1,2,4-triazolo and pyridines 7, 8 was achieved by cyclization of 2-hydrazino-3-nitropyridine 3a with formic acid.The 4,5,6,7-tetrahydro-1,2,4-triazolopyridine 13 and 8-amino-1,2,4-triazolopyridine 9 were obtained by catalytic hydrogenation.The reduction of triazolopyridine 8 using stannous chloride led to the intermediate compound 10 which with acetic anhydride afforded 8-acetylamino-5-chloro-1,2,4-triazolopyridine 10a.The structure of the derivatives was determined by 1H-nmr (DMSO-d6).