132461-40-6

Basic information

• Product Name: 3,4-Dimethyl-2-nitro-3H-imidazo[4,5-F]quinoline
• Synonyms: 3,4-dimethyl-2-nitroimidazo-(4,5-f)quinoline;2-Nitro-3,4-diMethyliMidazo[4,5-f]quinoline
• CAS NO: 132461-40-6
• Molecular Formula: C12H10N4O2
• Molecular Weight: 242.23
• Product Categories: Detergents;Mutagenesis Research Chemicals;Bases & Related Reagents;Heterocycles;Nucleotides;Heterocycles, Mutagenesis Research Chemicals, Nucleotides, Bases & Related Reagents
• Mol File: 132461-40-6.mol
• Article Data: 0

Chemical Properties

• Melting Point: 233-234°C
• Boiling Point: 502.7°Cat760mmHg
• Flash Point: 257.8°C
• Appearance: /
• Density: 1.47g/cm³
• Vapor Pressure: 3.12E-10mmHg at 25°C
• Refractive Index: 1.73
• Storage Temp.: Refrigerator
• PKA: 2.83±0.50(Predicted)
• CAS DataBase Reference: 3,4-Dimethyl-2-nitro-3H-imidazo[4,5-F]quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Dimethyl-2-nitro-3H-imidazo[4,5-F]quinoline(132461-40-6)
• EPA Substance Registry System: 3,4-Dimethyl-2-nitro-3H-imidazo[4,5-F]quinoline(132461-40-6)

Safety Data

• Hazardous Substances Data: 132461-40-6(Hazardous Substances Data)

Usage

Description

3,4-Dimethyl-2-nitro-3H-imidazo[4,5-F]quinoline, also known as MeIQ, is a nitro derivative of MeIQ, which is one of the food pyrolysis product mutagens and carcinogens. It is a grey-yellow solid with chemical properties that make it a significant compound in the field of toxicology and food safety.

Uses

Used in Research and Development:
3,4-Dimethyl-2-nitro-3H-imidazo[4,5-F]quinoline is used as a research compound for studying the effects of food pyrolysis products on human health. Its application in this field is crucial for understanding the mechanisms of mutagenicity and carcinogenicity associated with certain cooking methods and the substances they produce.
Used in Toxicology Studies:
In the field of toxicology, MeIQ is used as a model compound to investigate the toxic effects of food pyrolysis products. This helps researchers to develop strategies for reducing the formation of such harmful compounds in the food industry and to establish safety guidelines for food consumption.
Used in Analytical Chemistry:
3,4-Dimethyl-2-nitro-3H-imidazo[4,5-F]quinoline is used as a reference material in analytical chemistry for the development and validation of methods for detecting and quantifying mutagens and carcinogens in food products. This application is essential for ensuring the accuracy and reliability of analytical techniques used in food safety testing.
Used in Pharmaceutical Industry:
MeIQ is also used in the pharmaceutical industry as an adduct of MeIQ-nucleotide, which can be studied for its potential interactions with biological systems. This research can contribute to the development of new drugs or therapies targeting specific molecular pathways involved in mutagenicity and carcinogenicity.

InChI:InChI=1/C12H10N4O2/c1-7-6-9-8(4-3-5-13-9)10-11(7)15(2)12(14-10)16(17)18/h3-6H,1-2H3