13249-97-3

Basic information

• Product Name: Benzene, 2,4-dimethyl-1-[(4-methylphenyl)sulfonyl]-
• CAS NO: 13249-97-3
• Molecular Formula: C15H16O2S
• Molecular Weight: 260.357
• Mol File: 13249-97-3.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: Benzene, 2,4-dimethyl-1-[(4-methylphenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 2,4-dimethyl-1-[(4-methylphenyl)sulfonyl]-(13249-97-3)
• EPA Substance Registry System: Benzene, 2,4-dimethyl-1-[(4-methylphenyl)sulfonyl]-(13249-97-3)

Safety Data

• Hazardous Substances Data: 13249-97-3(Hazardous Substances Data)

Upstream product

• 4124-41-8 p-toluenesulfonylanhydride 
• 108-38-3 m-xylene 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 108-88-3 toluene 
• 38542-71-1 N-methylpyridinium p-toluenesulfonate 
• 70-55-3 toluene-4-sulfonamide 
• 599-89-3 4-chlorophenyl p-toluenesulfonate 
• 104-15-4 toluene-4-sulfonic acid 

Relevant articles and documents

Chloroaluminate Ionic Liquid Immobilized on Magnetic Nanoparticles as a Heterogeneous Lewis Acidic Catalyst for the Friedel–Crafts Sulfonylation of Aromatic Compounds

Chloroaluminate ionic liquid bound on magnetic nanoparticles (Fe3 O4 @O2 Si[PrMIM]Cl·AlCl3) was prepared and used as a heterogenous Lewis acidic catalyst for the Friedel–Crafts sulfonylation of aromatic compounds with sulfonyl chlorides or p-toluenesulfonic anhydride. The catalyst’s stability, efficiency, easy recovery, and high recyclability without considerable loss of catalytic capability after four recycles were evidence of its advantages. Furthermore, the stoichiometry, wide substrate scope, short reaction time, high yield of sulfones, and solvent-free reaction condition also made this procedure practical, ecofriendly, and economical.

The synthesis of diarylsulfones with simple arenes and K2S2O8 through double C-S bond formation

An unprecedented double C-S bond formation method has been developed to prepare both symmetric and unsymmetric diarylsulfones with simple arenes in a single step. This represents the first example that K2S2O8 can be employed as a highly effective sulfonating agent to synthesize diarylsulfones. The reaction demonstrates excellent reactivity, good functional group tolerance and high yields.

Sulfonylation of aromatic compounds with sulfonic acids using silica gel-supported AlCl3 as a heterogeneous Lewis acid catalyst

Silica gel-supported aluminum chloride (SiO2-AlCl3) has been shown to be a mild, efficient, and chemoselective heterogeneous Lewis acid catalyst for direct conversion of arenes to sulfones using sulfonic acids as sulfonylating agents. The catalyst can be prepared easily with cheap starting materials and is stable (as a bench-top catalyst) and reusable.