132548-91-5 Usage
Description
[1,1'-Binaphthalen]-2-ol, 2'-(diphenylphosphinyl)-, (1R)is a binaphthol derivative chemical compound with a molecular formula of C40H28O2P and a molecular weight of 580.61 g/mol. It is also known as (R)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl-6,6'-diol and is recognized for its role as a chiral ligand in asymmetric catalytic reactions.
Uses
Used in Asymmetric Catalytic Reactions:
[1,1'-Binaphthalen]-2-ol, 2'-(diphenylphosphinyl)-, (1R)is used as a chiral ligand for enhancing the selectivity and efficiency of various asymmetric catalytic reactions. Its application is crucial in achieving the desired enantiomeric excess, which is essential for the synthesis of biologically active compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, [1,1'-Binaphthalen]-2-ol, 2'-(diphenylphosphinyl)-, (1R)is used as a catalyst for the enantioselective synthesis of a variety of compounds. This ability is vital for producing single-enantiomer drugs, which can have significant implications on the drug's efficacy and safety.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, [1,1'-Binaphthalen]-2-ol, 2'-(diphenylphosphinyl)-, (1R)is employed as a catalyst for the enantioselective synthesis of active ingredients in pesticides and other agrochemical products. This ensures the production of enantiomerically pure compounds, which can help reduce environmental impact and improve the effectiveness of these products.
Check Digit Verification of cas no
The CAS Registry Mumber 132548-91-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,5,4 and 8 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 132548-91:
(8*1)+(7*3)+(6*2)+(5*5)+(4*4)+(3*8)+(2*9)+(1*1)=125
125 % 10 = 5
So 132548-91-5 is a valid CAS Registry Number.
132548-91-5Relevant articles and documents
Asymmetric ketone hydroboration catalyzed by alkali metal complexes derived from BINOL ligands
Carden, Jamie L.,Melen, Rebecca L.,Newman, Paul D.,Ruddy, Adam J.,Willcox, Darren
supporting information, p. 2417 - 2420 (2020/03/05)
The ability of alkali metal complexes featuring functionalized BINOL-derived ligands to catalyze ketone hydroboration reactions was explored. The reduced products were formed in excellent yields and with variable enantioselectivities dependent upon the nature of the ligand and the alkali metal cation.
Chiral Bifunctional Phosphine-Carboxylate Ligands for Palladium(0)-Catalyzed Enantioselective C?H Arylation
Yang, Lei,Neuburger, Markus,Baudoin, Olivier
supporting information, p. 1394 - 1398 (2018/01/05)
Previous enantioselective Pd0-catalyzed C?H activation reactions proceeding via the concerted metalation-deprotonation mechanism employed either a chiral ancillary ligand, a chiral base, or a bimolecular mixture thereof. This study describes th
Palladium-catalyzed R2(O)P directed C(sp2)-H acetoxylation
Zhang, Heng,Hu, Rong-Bin,Zhang, Xiao-Yu,Li, Shi-Xia,Yang, Shang-Dong
supporting information, p. 4686 - 4689 (2014/05/06)
A novel and efficient Pd-catalyzed C-H acetoxylation is described. The approach uses R2(O)P as a directing group to synthesize various substituted 2′-phosphorylbiphenyl-2-OAc compounds. Notably, the reaction exhibits smooth operation under mild conditions and shows good functional group tolerance. Products are obtained with high selectivity and yields. This journal is the Partner Organisations 2014.
