132611-42-8

Basic information

• Product Name: 3-(3-methylaminopropyl)-5-(4-methoxyphenyl)-1,2,4-thiadiazole
• CAS NO: 132611-42-8
• Molecular Weight: 263.363
• Mol File: 132611-42-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(3-methylaminopropyl)-5-(4-methoxyphenyl)-1,2,4-thiadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-methylaminopropyl)-5-(4-methoxyphenyl)-1,2,4-thiadiazole(132611-42-8)
• EPA Substance Registry System: 3-(3-methylaminopropyl)-5-(4-methoxyphenyl)-1,2,4-thiadiazole(132611-42-8)

Safety Data

• Hazardous Substances Data: 132611-42-8(Hazardous Substances Data)

Upstream product

• 105878-20-4 4-Methoxy-N-[1-methyl-pyrrolidin-(2Z)-ylidene]-thiobenzamide 
• 185-80-8 1-oxa-2-azaspiro[2.5]octane 
• 132611-45-1 {3-[5-(4-Methoxy-phenyl)-[1,2,4]thiadiazol-3-yl]-propyl}-methyl-amine; hydrochloride 

Downstream Products

• 132611-45-1 {3-[5-(4-Methoxy-phenyl)-[1,2,4]thiadiazol-3-yl]-propyl}-methyl-amine; hydrochloride 
• 132611-51-9 3-(3-dimethylaminopropyl)-5-(4-methoxyphenyl)-1,2,4-thiadiazole hydroiodide 

Relevant articles and documents

Ring transformations of semicyclic 1,3-dicarbonyl heteroanalogs; IV. Synthesis of 3-(ω-aminoalkyl)-1,2,4-thiadiazoles by ring transformation reaction of semicyclic thioacylamidines with 3,3-pentamethyleneoxaziridine

Semicyclic thioacylamidines 1 react with 3,3-pentamethylene-oxaziridine by ring transformation affording novel ω-aminoalkyl-1,2,4-thiadiazoles 5, which are conveniently isolated as hydrochlorides 6. These can be transformed to the corresponding free bases 5, which in one case are methylated at the amino group to give an ω-dimethylaminoalkyl-1,2,4-thiadiazole 7.