132616-38-7Relevant articles and documents
ENZYME-CATALYSED ASYMMETRIC SYNTHESIS OF A SPIROHEPTANE DERIVATIVEWITH AXIAL CHIRALITY AND ENZYMATIC RESOLUTION OF RACEMIC SPIROHEPTANE DERIVATIVES
Naemura, Koichiro,Furutani, Atsushi
, p. 3215 - 3217 (2007/10/02)
2,6-Bis(acetoxymethyl)-2,6-bis(hydroxymethyl)spiroheptane with axial chirality and moderate optical purity has been prepared in high chemical yield by pig liver esterase-catalysed asymmetric hydrolyses of 2,2,6,,6-tetrakis(acetoxymethyl)spiroheptane.Similarly, racemic 2,6-disubstituted spiroheptane derivatives with axial chirality were resolved by enantioselective enzime-catalysed hydrolyses.