132727-07-2

Basic information

• Product Name: 2,6-di(3-pyridylmethylidene)cyclohexanone
• Synonyms: 2,6-di(3-pyridylmethylidene)cyclohexanone
• CAS NO: 132727-07-2
• Molecular Weight: 276.338
• Mol File: 132727-07-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,6-di(3-pyridylmethylidene)cyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-di(3-pyridylmethylidene)cyclohexanone(132727-07-2)
• EPA Substance Registry System: 2,6-di(3-pyridylmethylidene)cyclohexanone(132727-07-2)

Safety Data

• Hazardous Substances Data: 132727-07-2(Hazardous Substances Data)

Upstream product

• 500-22-1 3-pyridinecarboxaldehyde 
• 108-94-1 cyclohexanone 

Relevant articles and documents

A temperature study on a stereoselective organocatalyzed aldol reaction in water

We report the first temperature study on the stereoselectivity of the 'in-water' aldol reaction between nicotinaldehyde (3-pyridinecarbaldehyde) and cyclohexanone catalyzed by morpholine and trans-4-tert-butyldimethylsilyloxy-l-proline. Eyring plots of diastereomeric ratio anti/syn gave a constant diastereoselectivity with respect to reaction temperature using morpholine as catalyst. With O(TBS)-l-proline we observed a non-linear behaviour of the Eyring plot with the presence of an inversion temperature (Tinv), which disclosed dynamic solvation effects in water.

SMALL MOLECULE STIMULATORS OF STEROID RECEPTOR COACTIVATOR PROTEINS AND THEIR USE IN THE TREATMENT OF CANCER

Small molecule stimulators of steroid receptor coactivator (SRC) family proteins are provided, as well as methods for their use in treating or preventing cancer. Also provided are methods for stimulating SRC family proteins in a cell.