132819-56-8

Basic information

• Product Name: 3-Methyl-4-phenyl-4H-pyridine-1-carboxylic acid ethyl ester
• Synonyms: 3-Methyl-4-phenyl-4H-pyridine-1-carboxylic acid ethyl ester
• CAS NO: 132819-56-8
• Molecular Weight: 243.305
• Mol File: 132819-56-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Methyl-4-phenyl-4H-pyridine-1-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methyl-4-phenyl-4H-pyridine-1-carboxylic acid ethyl ester(132819-56-8)
• EPA Substance Registry System: 3-Methyl-4-phenyl-4H-pyridine-1-carboxylic acid ethyl ester(132819-56-8)

Safety Data

• Hazardous Substances Data: 132819-56-8(Hazardous Substances Data)

Upstream product

• 108-99-6 3-Methylpyridine 
• 591-50-4 iodobenzene 
• 132368-30-0 N-ethoxycarbonyl-3-methylpyridinium chloride 

Downstream Products

• 2052-92-8 3-methyl-4-phenyl-pyridine 
• 623-53-0 ethyl methyl carbonate 

Relevant articles and documents

Regioselective Addition ofd Copper-Zinc Aryl Organometallic Reagents to 3-substituted Pyridinium Salts

A number of 3-substituted pyridinium salts are subjected to nucleophilic addition by copper-zinc aryl organometallic reagents.The adducts are oxidized subsequently to form the corresponding 4-arylpyridines.In all the cases 1,4-addition products are obtained predominantly.The regioselectivity can be rationalized according to the hard-soft acid-base principle.Calculations on both charge distributions and FMO coefficients indicate that these reactions may be classified on the basis of the type of soft acid-soft base reactions.The observed γ-attack complies very well with the orientation of the FMO coefficients as estimated by a semiempirical method.