132847-82-6Relevant articles and documents
Conversion of Dipeptides and a Tetrapeptide to Macrocyclic Ionophores by means of Caesium Aided Ring Closure of the N-2-Chloroacetyl Derivatives
Kruizinga, Wim H.,Kingma, Rob,Leegstra, Libbe,Rokaszewski, Edward,Gruppen, Gert,Kellogg, Richard M.
, p. 1647 - 1648 (2007/10/02)
Three di-, (Gly)2, (Val)2 and (Leu)2, and one tetrapeptide, (Gly)4, have been acylated with 2-chloroacetyl chloride and the resulting products treated with Cs2CO3 in the dimethylformamide (DMF) solution; (Gly)2 and (Leu)2 provided strained 9-membered rings whereas (Val)2 dimerized to the 18-membered ring.