132868-33-8

Basic information

• Product Name: 3-Methoxyglutaric anhydride
• Synonyms: 3-Methoxyglutaric anhydride
• CAS NO: 132868-33-8
• Molecular Formula: C6H8O4
• Molecular Weight: 144.12532
• Mol File: 132868-33-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 271.6±33.0 °C(Predicted)
• Appearance: /
• Density: 1.23±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 3-Methoxyglutaric anhydride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methoxyglutaric anhydride(132868-33-8)
• EPA Substance Registry System: 3-Methoxyglutaric anhydride(132868-33-8)

Safety Data

• Hazardous Substances Data: 132868-33-8(Hazardous Substances Data)

Upstream product

• 4126-54-9 dimethyl 3-methoxyglutaric acid 
• 7250-55-7 dimethyl 3-hydroxypentanedioate 
• 152294-13-8 2-methoxypropane-1,3-dicarboxylic acid 

Relevant articles and documents

Enzymes in Organic Synthesis, 18. Lipase-Catalyzed Asymmetric Alcoholysis of 3-Substituted Pentanedioic Anhydrides

The influence of several enzymes, alcohols, and solvents on the stereochemical outcome of the asymmetric alcoholysis of 3-substituted pentanedioic anhydrides was investigated.The alcoholysis of 3-acetoxypentanedioic anhydride (5a) in diethyl ether with 2-methylpropanol afforded the (3S)-monoester (S)-6a with an enantiomeric excess of >98percent when the lipase from Candida sp. 382 was used as the enzyme.Under the same conditions, 3-methoxypentanedioic anhydride (5c) was converted by the lipase of Pseudomonas cepacia (Amano PS) into the (3R)-monoester (R)-6c with an e.e. of 90percent.Key Words: Enzymes / Lipases / Pentanedioic anhydrides / Alcoholysis, asymmetric / Pentanedioates