132924-59-5

Basic information

• Product Name: 3-[(4-Chlorophenyl)thio]-1-(diphenylmethyl)azetidine
• Synonyms: 3-[(4-Chlorophenyl)thio]-1-(diphenylmethyl)azetidine;1-benzhydryl-3-(4-chlorophenyl)sulfanylazetidine
• CAS NO: 132924-59-5
• Molecular Formula: C₂₂H₂₀ClNS
• Molecular Weight: 365.9189
• Mol File: 132924-59-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 477.8±45.0 °C(Predicted)
• Appearance: /
• Density: 1.26±0.1 g/cm3(Predicted)
• PKA: 6.40±0.10(Predicted)
• CAS DataBase Reference: 3-[(4-Chlorophenyl)thio]-1-(diphenylmethyl)azetidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[(4-Chlorophenyl)thio]-1-(diphenylmethyl)azetidine(132924-59-5)
• EPA Substance Registry System: 3-[(4-Chlorophenyl)thio]-1-(diphenylmethyl)azetidine(132924-59-5)

Safety Data

• Hazardous Substances Data: 132924-59-5(Hazardous Substances Data)

Upstream product

• 33301-41-6 1-benzhydryl-3-azetidinyl methanesulfonate 
• 106-54-7 p-Chlorothiophenol 
• 18621-17-5 1-(diphenylmethyl)-3-hydroxyazetidine 
• 108-20-3 di-isopropyl ether 
• 6153-56-6 oxalic acid dihydrate 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 132924-61-9 3-[(4-chlorophenyl)thio]-1-azetidinecarbonyl chloride 
• 1340259-48-4 3-(4-chloro-phenylsulfanyl)-azetidine 
• 848643-97-0 1-benzhydryl-3-(4-chloro-benzenesulfinyl)-azetidine 

Relevant articles and documents

1,3-DISUBSTITUTED AZETIDINE DERIVATIVES FOR USE AS CCR-3 RECEPTOR ANTAGONISTS IN THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISEASES

Compounds of formula Ia or Ib in free or salt form, wherein Ar, X1, X2, m, R1, Q, Y, R2 and R3 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by CCR-3, for example an inflammatory or allergic cond

Method of treating muscular tension, muscle spasticity and anxiety with 3-aryloxy and 3-arylthioazetidinecarboxamides

A method of treating animals to obtain muscle relaxation and/or to relieve anxiety is disclosed utilizing novel and known 3-aryloxy and 3-arylthioazetidinecarbonxamides having the formula: STR1 wherein Z is oxygen or sulfur; B is oxygen or sulfur; Ar is pyridyl or halo substituted pyridyl, phenyl or substituted phenyl; R1 and R2 are hydrogen, loweralkyl, aryl, allyl groups, propargyl, cycloalkyl, loweralkylcycloalkyl, cycloakylloweralkyl, arylloweralkyl and diloweralkylaminoalkyl, and R1 and R2 when taken together with the adjacent nitrogen atom may form a heterocyclic amine radical; R3 is hydrogen, loweralkyl, aryl or arylloweralkyl, and the geometrical isomers thereof and pharmaceutical salts thereof and hydrates thereof when they are possible.