13293-47-5 Usage
Description
(+)-ISOPINOCAMPHEYLAMINE, also known as (1S,2S,3S,5R)-(+)-isopinocampheylamine, is a primary bicyclic amine with potent M2 ion channel inhibitor ability. It is structurally similar to amantadine and has shown promise as a candidate for developing anti-influenza agents due to its ability to inhibit the M2 ion channel, which is crucial for the replication of the influenza virus.
Uses
Used in Pharmaceutical Industry:
(+)-ISOPINOCAMPHEYLAMINE is used as an active pharmaceutical ingredient for the development of anti-influenza agents. Its potent M2 ion channel inhibitor ability makes it a promising candidate for creating new medications to combat influenza viruses, particularly those strains resistant to existing antiviral drugs.
Used in Antiviral Research:
(+)-ISOPINOCAMPHEYLAMINE is used as a key compound in antiviral research, specifically targeting the M2 ion channel of the influenza virus. Its structural similarity to amantadine allows researchers to study its interactions with the virus and develop new strategies for inhibiting viral replication and transmission.
Check Digit Verification of cas no
The CAS Registry Mumber 13293-47-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,2,9 and 3 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 13293-47:
(7*1)+(6*3)+(5*2)+(4*9)+(3*3)+(2*4)+(1*7)=95
95 % 10 = 5
So 13293-47-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H19N/c1-6-8-4-7(5-9(6)11)10(8,2)3/h6-9H,4-5,11H2,1-3H3/t6-,7+,8-,9-/m0/s1
13293-47-5Relevant articles and documents
Organoboranes for synthesis. 16. A convenient synthesis of enantiomerically pure isopinocampheylamine, a chiral derivatizing agent for gas chromatographic analysis of optically active carboxylic acids
Ramachandran, P. Veeraraghavan,Rangaishenvi, Milind V.,Singaram, Bakthan,Goralski, Christian T.,Brown, Herbert C.
, p. 341 - 345 (1996)
Both isomers of enantiomerically pure isopinocampheylamine (1) have been synthesized from the corresponding B-chlorodiisopinocampheylborane by treatment with either methylmagnesium bromide or trimethylaluminum to form B-methyldiisopinocampheylborane, followed by treatment of the intermediate with hydroxylamine-O-sulfonic acid. Application of 1 as a derivatizing agent for the gas chromatographic analysis of optically active carboxylic acids has been demonstrated.