1329489-81-7

Basic information

• Product Name: (2-chloro-9H-fluoren-9-yl)methyl 4-methoxybenzylcarbamate
• Synonyms: (2-chloro-9H-fluoren-9-yl)methyl 4-methoxybenzylcarbamate
• CAS NO: 1329489-81-7
• Molecular Weight: 393.87
• Mol File: 1329489-81-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2-chloro-9H-fluoren-9-yl)methyl 4-methoxybenzylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: (2-chloro-9H-fluoren-9-yl)methyl 4-methoxybenzylcarbamate(1329489-81-7)
• EPA Substance Registry System: (2-chloro-9H-fluoren-9-yl)methyl 4-methoxybenzylcarbamate(1329489-81-7)

Safety Data

• Hazardous Substances Data: 1329489-81-7(Hazardous Substances Data)

Upstream product

• 57486-69-8 methyl 2-(2-bromophenyl)acetate 
• 18698-97-0 ortho-bromophenylacetic acid 
• 1329489-84-0 methyl 2-(4'-chlorobiphenyl-2-yl)acetate 
• 1329489-24-8 methyl 2-(4'-chlorobiphenyl-2-yl)diazoacetate 

Downstream Products

• 2393-23-9 4-methoxy-benzylamine 

Relevant articles and documents

Intramolecular aromatic carbenoid insertion of biaryldiazoacetates for the regioselective synthesis of fluorenes

The rhodium- or copper-catalyzed intramolecular aromatic carbenoid insertion of biaryldiazoacetates offers a convenient route to fluorene carboxylates with high yields. Whereas, thermal conditions provided a mixture of two regioisomeric products when substituted biaryldiazoacetates were employed as substrates. The developed catalytic conditions displayed an excellent level of regioselectivity, presumably owing to steric effects. The insertion mechanism was assumed to be an electrophilic aromatic substitution, which was supported by preliminary mechanistic studies. A chloro-substituted fluorene derivative was efficiently synthesized and utilized as a base-sensitive protecting group of amines.