132980-39-3Relevant articles and documents
Electro-oxidative C(sp3)-H Amination of Azoles via Intermolecular Oxidative C(sp3)-H/N-H Cross-Coupling
Wu, Jiwei,Zhou, Yi,Zhou, Yuchen,Chiang, Chien-Wei,Lei, Aiwen
, p. 8320 - 8323 (2017)
A method for electrooxidative C(sp3)-H amination via intermolecular oxidative C(sp3)-H/N-H cross-coupling has been developed under metal- and oxidant-free conditions. The C(sp3)-H bonds adjacent to oxygen, nitrogen, and sulfur atoms could all react smoothly with various amines to give the corresponding products with moderate to good yields (30-93%). In addition, the C(sp3)-H bonds of benzylic and allylic are also tolerated in this reaction. A preliminary mechanistic study indicates that the C-H cleavage of tetrahydrofuran is probably not involved in the rate-determining step.
Metal-free cross-dehydrogenative C–N coupling of azoles with xanthenes and related activated arylmethylenes
Li, Yanni,Li, Yanping,Li, Yuan,Chen, Chunlin,Ying, Fengyuan,Dong, Ying,Liang, Deqiang
supporting information, p. 2053 - 2065 (2019/05/29)
A metal-free C(sp3)–H/N–H cross-coupling of azoles with xanthenes and related activated arylmethylenes is presented. Both the use of azoles and the activation pattern of C(sp3)–H sources are essential for this transformation. In the