1330113-26-2

Basic information

• Product Name: 2'-O-[phenoxy(thiocarbonyl)]-3',5'-O-triacetyl-2-chloroadenosine
• Synonyms: 2'-O-[phenoxy(thiocarbonyl)]-3',5'-O-triacetyl-2-chloroadenosine
• CAS NO: 1330113-26-2
• Molecular Weight: 521.938
• Mol File: 1330113-26-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2'-O-[phenoxy(thiocarbonyl)]-3',5'-O-triacetyl-2-chloroadenosine(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-O-[phenoxy(thiocarbonyl)]-3',5'-O-triacetyl-2-chloroadenosine(1330113-26-2)
• EPA Substance Registry System: 2'-O-[phenoxy(thiocarbonyl)]-3',5'-O-triacetyl-2-chloroadenosine(1330113-26-2)

Safety Data

• Hazardous Substances Data: 1330113-26-2(Hazardous Substances Data)

Upstream product

• 146-77-0 2-Chloroadenosine 
• 1246384-63-3 3',5'-O-triacetyl-2-chloroadenosine 
• 1005-56-7 phenylcarbonochloridothioate 

Downstream Products

• 4291-63-8 2-chloro-2'-deoxyadenosine 

Relevant articles and documents

A new synthesis of 2-chloro-2'-deoxyadenosine (Cladribine), CdA)

A new efficient route for the synthesis of 2-chloro-2';-deoxyadenosine (Cladribine), CdA) has been developed. The key step of this method was selective deprotection of the acetyl group at the 2' position; the 3', 5' acetyl groups were not affected. This can be accomplished efficiently with hydroxylamine hydrochloride and sodium acetate in pyridine. The 2' hydroxyl group was removed by the Barton-McCombie reaction. Using this strategy, CdA was prepared in five steps and 31.0% yields. Copyright Taylor and Francis Group, LLC.