13314-74-4

Basic information

• Product Name: 4-(cyclohex-1-en-1-yl)-N,N-dimethylaniline
• CAS NO: 13314-74-4
• Molecular Formula: C₁₄H₁₉N
• Molecular Weight: 201.3074
• Mol File: 13314-74-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 315.8°C at 760 mmHg
• Flash Point: 128.6°C
• Density: 1.006g/cm³
• Vapor Pressure: 0.000428mmHg at 25°C
• Refractive Index: 1.574
• CAS DataBase Reference: 4-(cyclohex-1-en-1-yl)-N,N-dimethylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(cyclohex-1-en-1-yl)-N,N-dimethylaniline(13314-74-4)
• EPA Substance Registry System: 4-(cyclohex-1-en-1-yl)-N,N-dimethylaniline(13314-74-4)

Safety Data

• Hazardous Substances Data: 13314-74-4(Hazardous Substances Data)

Upstream product

• 108-94-1 cyclohexanone 
• 121-69-7 N,N-dimethyl-aniline 
• 67-64-1 acetone 
• 7647-01-0 hydrogenchloride 
• 33930-10-8 4-(1-(4-(dimethylamino)phenyl)cyclohexyl)-N,N-dimethylaniline 
• 586-77-6 4-bromo-N,N-dimethylaniline 
• 22718-22-5 cyclohex-1-en-1-yl dimethylcarbamate 
• 7353-91-5 4-dimethylaminophenylmagnesium bromide 
• 930-66-5 1-chlorocyclohexene 
• 7570-92-5 cyclohexyl phenyl sulphide 
• 13299-39-3 1-[4-(dimethylamino)phenyl]cyclohexanol 

Downstream Products

• 13299-39-3 1-[4-(dimethylamino)phenyl]cyclohexanol 

Relevant articles and documents

Photoinduced Deaminative Borylation of Unreactive Aromatic Amines Enhanced by CO2

Herein, direct unreactive C-N borylation of aromatic amines by a photocatalyst was achieved. The C-N borylation of aromatic amines with bis(pinacolato)diboron (B2pin2) proceeded using a pyrene catalyst under light irradiation to afford desired borylated products and aminoborane as a byproduct. The yield of the borylated product improved under a CO2 atmosphere which probably reduced the inhibitory effect of aminoborane. Mechanistic studies suggested that the C-N bond cleavage and C-B bond formation proceeded via a concerted pathway.

Pd-catalyzed cross-coupling of highly sterically congested enol carbamates with grignard reagents via c-o bond activation

The palladium-catalyzed cross-coupling reaction of enol carbamates to construct highly sterically congested alkenyl compounds is presented for the first time. This protocol demonstrates the potential of using thermally stable and highly atom-economic enol electrophiles as building blocks in bulky alkene synthesis. This reaction accommodates a broad substrate scope with excellent Z/E isomer ratios, which also provides a new synthetic pathway for accessing Tamoxifen.

Amido pincer nickel catalyzed kumada cross-coupling of aryl, heteroaryl, and vinyl chlorides

Amido pincer nickel complexes {Ni(Cl)[2-P(Ph2)C 6H4NC(Ph)=NAr]} (Ar = 4-MeC6H4, 1; Ar = 4-ClC6H4, 2; Ar = 4-MeOC6H4, 3) were shown to efficiently catalyze the cross-coupling of activated, unactivated, and deactivated aryl chlorides, N-heteroaryl chlorides, 1,4-dichlorobenzene, and vinyl chlorides with aryl Grignard reagents. Georg Thieme Verlag Stuttgart, New York.