133149-48-1

Basic information

• Product Name: (E)-3-(4-Methoxy-phenyl)-2-(4-oxo-3,4-dihydro-quinazolin-2-yl)-acrylonitrile
• Synonyms: (E)-3-(4-Methoxy-phenyl)-2-(4-oxo-3,4-dihydro-quinazolin-2-yl)-acrylonitrile
• CAS NO: 133149-48-1
• Molecular Weight: 303.32
• Mol File: 133149-48-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-3-(4-Methoxy-phenyl)-2-(4-oxo-3,4-dihydro-quinazolin-2-yl)-acrylonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(4-Methoxy-phenyl)-2-(4-oxo-3,4-dihydro-quinazolin-2-yl)-acrylonitrile(133149-48-1)
• EPA Substance Registry System: (E)-3-(4-Methoxy-phenyl)-2-(4-oxo-3,4-dihydro-quinazolin-2-yl)-acrylonitrile(133149-48-1)

Safety Data

• Hazardous Substances Data: 133149-48-1(Hazardous Substances Data)

Upstream product

• 622847-77-2 2-(4-oxo-3,4-dihydro-2-quinazolinyl)-2-(tetrahydro-2-furanylidene)acetonitrile 
• 123-11-5 4-methoxy-benzaldehyde 
• 118-92-3 anthranilic acid 
• 39145-31-8 2-cyano-3-(4-methoxyphenyl)thioacrylamide 
• 133149-53-8 (Z)-2-Cyano-3-(4-methoxy-phenyl)-thioacrylimidic acid methyl ester 
• 30750-23-3 2-(4-oxo-3,4-dihydroquinazolin-2-yl)acetonitrile 

Downstream Products

• 133149-61-8 9-Amino-8-benzoyl-7-(4-methoxy-phenyl)-11-oxo-11H-pyrido[2,1-b]quinazoline-6-carbonitrile 
• 133149-65-2 7-(4-Methoxy-phenyl)-9,11-dioxo-8,11-dihydro-9H-pyrido[2,1-b]quinazoline-6,8-dicarbonitrile 
• 133149-57-2 9-Amino-7-(4-methoxy-phenyl)-11-oxo-11H-pyrido[2,1-b]quinazoline-6,8-dicarbonitrile 

Relevant articles and documents

Reaction of 2-hetaryl-2-(tetrahydro-2-furanylidene)acetonitriles with aldehydes

The reaction of 2-hetaryl-2-(tetrahydro-2-furanylidene)acetonitriles with a electrophilic reagent (anisaldehyde) was studied. It was shown that condensation of the latter with 2-(4-oxo-3,4-dihydro-2-quinazolyl)- and 2-(1H-benzo[d]imidazol-2-yl)-2-(tetrahydro-2-furanylidene)acetonitriles in the presence of secondary amines or acids takes place with elimination of the furan fragment and the formation of 3-aryl-2-(4-oxo-3,4-dihydro-2-quinazolinyl)- and 2-(1H-benzo[d]imidazol-2-yl)acrylo-nitriles.