1331777-74-2

Basic information

• Product Name: cis-4-AMino-1-Boc-3-hydro...
• Synonyms: cis-4-AMino-1-Boc-3-hydro...;cis-4-AMino-1-Boc-3-hydroxypiperidine;cis-tert-Butyl 4-amino-3-hydroxypiperidine-1-carboxylate;(3R,4S)-rel-tert-Butyl 4-amino-3-hydroxypiperidine-1-carboxylate
• CAS NO: 1331777-74-2
• Molecular Formula: C10H20N2O3
• Molecular Weight: 216.28
• Mol File: 1331777-74-2.mol
• Article Data: 21

Chemical Properties

• Appearance: /
• CAS DataBase Reference: cis-4-AMino-1-Boc-3-hydro...(CAS DataBase Reference)
• NIST Chemistry Reference: cis-4-AMino-1-Boc-3-hydro...(1331777-74-2)
• EPA Substance Registry System: cis-4-AMino-1-Boc-3-hydro...(1331777-74-2)

Safety Data

• Hazardous Substances Data: 1331777-74-2(Hazardous Substances Data)

Usage

General Description

Cis-4-Amino-1-Boc-3-hydroxypiperidine is a chemical compound with the molecular formula C11H21N3O3. It is a derivative of piperidine and contains an amino group and a Boc (tert-butoxycarbonyl) protecting group. cis-4-AMino-1-Boc-3-hydro... is commonly used in organic synthesis as a building block for the preparation of various pharmaceuticals and bioactive molecules. It can also be utilized in the production of peptide and peptide-like structures. The Boc protecting group allows for selective deprotection and further functionalization of the molecule, making it a valuable tool in synthetic chemistry.

Upstream product

• 1130156-23-8 (±)-tert-butyl 3-hydroxy-4-oxopiperidine-1-carboxylate 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 83763-31-9 1-phenylmethyl-3-hydroxy-4,4-dimethoxypiperidine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1161932-02-0 trans-4-Benzylamino-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester 
• 167832-25-9 trans(±)benzyl-4-azido-3-hydroxypiperidine-1-carboxylate 
• 959617-87-9 benzyl (3R,4R)-4-amino-3-hydroxy-piperidine-1-carboxylate 
• 1161931-95-8 (3R,4R)-4-benzylamino-3-hydroxy-4-piperidine-1-carboxylic acid tert-butyl ester 
• 161157-50-2 tert-butyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate 
• 85838-94-4 N-Boc-1,2,3,6-tetrahydropyridine 
• 1427170-50-0 C₁₁H₂₀N₂O₄ 
• 71233-28-8 3-hydroxypiperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester 
• 71233-25-5 ethyl 1-tert-butoxycarbonyl-3-oxopiperidine-4-carboxylate 
• 203503-02-0 tert-butyl (3RS,4RS)-4-azido-3-hydroxy-piperidine-1-carboxylate 

Downstream Products

• 1007596-96-4 (3R,4R)-tert-butyl 3-azido-4-[(diphenylmethylene)amino]piperidine-1-carboxylate 
• 1565846-67-4 C₁₈H₂₆BrN₃O₃ 
• 1565853-00-0 C₁₆H₃₀N₂O₃ 

Relevant articles and documents

TBK/IKK INHIBITOR COMPOUNDS AND USES THEREOF

The present invention relates to compounds of Formula I and pharmaceutically acceptable compositions thereof, useful as TBK/IKKε inhibitors.

PYRROLO[2,3-D]PYRIMIDINYL, PYRROLO[2,3-B]PYRAZINYL AND PYR-ROLO[2,3-D]PYRIDINYL ACRYLAMIDES

The present invention provides pharmaceutically active pyrrolo[2,3-d]pyrimidinyl and pyrrolo[2,3-d]pyridinyl acrylamides and analogues thereof. Such compounds are useful for inhibiting Janus Kinase (JAK). This invention also is directed to compositions comprising methods for making such compounds, and methods for treating and preventing conditions mediated by JAK.

METHYLPYRROLOPYRIMIDINECARBOXAMIDES

The compounds of Formula (I), wherein R1, R2, R21, R22, R23, R24, Y and R3 have the meanings as given in the description, the salts thereof, the stereoisomers of the compounds and the salts thereof are effective inhibitors of the type 5 phosphodiesterase.