13326-72-2

Basic information

• Product Name: Benzaldehyde, 4-methoxy-3,5-bis(phenylmethoxy)-
• CAS NO: 13326-72-2
• Molecular Formula: C22H20O4
• Molecular Weight: 348.398
• Mol File: 13326-72-2.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 4-methoxy-3,5-bis(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 4-methoxy-3,5-bis(phenylmethoxy)-(13326-72-2)
• EPA Substance Registry System: Benzaldehyde, 4-methoxy-3,5-bis(phenylmethoxy)-(13326-72-2)

Safety Data

• Hazardous Substances Data: 13326-72-2(Hazardous Substances Data)

Upstream product

• 13326-71-1 3,5-dibenzoyloxy-4-methoxybenzoic acid 2-benzenesulfonylhydrazide 
• 149-91-7 3,4,5-trihydroxybenzoic acid 
• 13326-70-0 3,5-Bisbenzyloxy-4-methoxybenzoic acid hydrazide 
• 99-24-1 methyl galloate 
• 100-44-7 benzyl chloride 
• 24093-81-0 methyl 3,5-dihydroxy-4-methoxybenzoate 
• 13326-69-7 methyl 3,5-bis(benzyloxy)-4-methoxybenzoate 
• 27229-56-7 [3,5-bis(benzyloxy)-4-methoxyphenyl]methanol 

Downstream Products

• 901125-34-6 ethyl (E)-3,5-bis(benzyloxy)-4-methoxycinnamate 
• 1969289-10-8 (+)-celosine 
• 129724-43-2 (E)-1-(2,4-dihydroxy-3,6-dimethoxyphenyl)-3-phenylprop-2-en-1-one 
• 20032-42-2 2,5-dimethoxyresorcinol 
• 6274-74-4 2,6-dibenzyloxy-1,4-dimethoxybenzene 
• 1262680-48-7 C₂₄H₂₄O₄ 
• 80545-27-3 5,7,3',5'-tetrabenzyloxy-4'-methoxyisoflavone 
• 76265-28-6 5,7,3',5'-tetrahydroxy-4'-methoxyisoflavon (junipegenin-A) 
• 138566-62-8 (2RS,3SR)-(4-benzyloxy-3,5-dimethoxyphenyl)-1-(3,5-dibenzyloxy-4-methoxyphenyl)-2,3-dimethylbutan-1-one 
• 138566-62-8 (2RS,3RS)-(4-benzyloxy-3,5-dimethoxyphenyl)-1-(3,5-dibenzyloxy-4-methoxyphenyl)-2,3-dimethylbutan-1-one 
• 138566-67-3 (1RS,2SR,3RS)-4-(4-benzyloxy-3,5-dimethoxyphenyl)-1-(3,5-dibenzyloxy-4-methoxyphenyl)-2,3-dimethylbutyl acetate 
• 138566-67-3 (1RS,2RS,3SR)-4-(4-benzyloxy-3,5-dimethoxyphenyl)-1-(3,5-dibenzyloxy-4-methoxyphenyl)-2,3-dimethylbutyl acetate 
• 138566-61-7 4-(4-benzyloxy-3,5-dimethoxyphenyl)-1-(3,5-dibenzyloxy-4-methoxyphenyl)-3-methylbutan-1-one 
• 138566-68-4 (1RS,2RS,3SR)-1-(3,5-dihydroxy-4-methoxyphenyl)-4-(4-hydroxy-3,5-dimethoxyphenyl)-2,3-dimethylbutyl acetate 

Relevant articles and documents

New odorless method for the Corey-Kim and Swern oxidations utilizing dodecyl methyl sulfide (Dod-S-Me)

Development of the odorless dodecyl methyl sulfide (Dod-S-Me, 1) as an alternative for dimethyl sulfide (DMS) and new odorless methods for the Corey-Kim and Swern oxidations are described. These reactions have been developed with a view toward green chemistry, utilizing Dod-S-Me (1) and common solvents instead of dichloromethane.

Synthesis, crystal structure, and growth inhibition of human hepatoma cell (HepG2) of polyphenolic compounds based on gallates

Seven compounds (1-7) based on gallate were synthesized and characterized by elemental analysis, 1H NMR, and MS spectra. 2-(3,5-Dibenzyloxy-4- methoxy)phenyl-2-propanol (6) was a new compound. Methyl 3,5-dihydroxy-4- methoxybenzoate (3), methyl 3,5-dibenzyloxy-4-methoxybenzoate (4), 3,5-dibenzyloxy-4-methoxybenzyl alcohol (5), and compound 6 were structurally determined by single-crystal X-ray diffraction for the first time. Crystallography data for 3: space group P21212 1; a = 4.0750(8) A, b = 7.5880(15) A, c = 29.802(6) A; V = 921.5(3) A3 Z = 4. 4: space group P-1; a = 10.068(2) A b = 10.499(2) A, c = 11.388(2) A; α = 76.84(3)°, β= 66.79(3)°, γ = 64.10(3)°; V = 993.0(3) A3, Z = 2. 5: space group P-1; a = 8.1410(16) A, b = 8.7590(18) A, c = 12.879(3) A; α = 91.66(3)°, β= 94.69(3)°, γ = 91.73(3)°; V = 914.4(3) A3; Z = 2. 6: space group P21/c; a = 5.8100(12) A, b = 15.778(3) A, c = 23.237(5) A; β= 96.09(3)°; V = 2118.1(7) A3; Z = 4. All of the seven compounds were evaluated for the inhibition of growth of human hepatoma (HepG2) cells. Comparison with the positive-control 5-fluorouracil (IC50 51.6 μmol/L), 5 showed stronger cytotoxic activity with an IC50 around 15.3 μmol/L, while IC50 value of 3 was 90.3 μmol/L. The effect of slight structural variations in this series of compounds was found to cause a marked change in their activity against HepG2 cells.

Development of Odorless Thiols and Sulfides and Their Applications to Organic Synthesis

Development of new odorless thiols (dodecanethiol, 4-n- heptylphenylmethanethiol, 4-trimethylsilylphenylmethanethiol, 4-trimethylsilylbenzenethiol) and an odorless sulfide (1-methylsulfanyldodecane) and their applications to dealkylation, Michael addition, Swern oxidation, and Corey-Kim oxidation are described.