133262-02-9

Basic information

• Product Name: Piperazine, 1-[3-(4-chlorophenyl)-3-(2,3-dimethoxyphenyl)-1-oxo-2-propenyl]-4-(3,4, 5-trimethoxybenzoyl)-, (E)-
• CAS NO: 133262-02-9
• Molecular Formula: C31H33ClN2O7
• Molecular Weight: 581.065
• Mol File: 133262-02-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Piperazine, 1-[3-(4-chlorophenyl)-3-(2,3-dimethoxyphenyl)-1-oxo-2-propenyl]-4-(3,4, 5-trimethoxybenzoyl)-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1-[3-(4-chlorophenyl)-3-(2,3-dimethoxyphenyl)-1-oxo-2-propenyl]-4-(3,4, 5-trimethoxybenzoyl)-, (E)-(133262-02-9)
• EPA Substance Registry System: Piperazine, 1-[3-(4-chlorophenyl)-3-(2,3-dimethoxyphenyl)-1-oxo-2-propenyl]-4-(3,4, 5-trimethoxybenzoyl)-, (E)-(133262-02-9)

Safety Data

• Hazardous Substances Data: 133262-02-9(Hazardous Substances Data)

Upstream product

• 133263-03-3 (E)-3-(4-chlorophenyl)-3-(2,3-dimethoxyphenyl)acrylic acid 

Relevant articles and documents

N-ACRYLOYLPIPERAZINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PAF ANTAGONISTS

Compounds of formula (I): STR1 wherein R 1 and R 2 is each--R 5,--CH=CH--R 5 or--C C--R 5, wherein R. sup.5 is optionally substituted aryl or aromatic heterocyclic; R 3 is hydrogen, alkyl, cyano or--R 5 ; X is oxygen or sulfur; A is 1,4-piperazin-1, 4-diyl or a 1,4-homopiperazin-1,4-diyl; B' is alkylene, carbonyl, thiocarbonyl, sulfinyl or sulfonyl; and R 4 is optionally substituted phenyl and pharmaceutically acceptable salts thereof have valuable PAF antagonist activity, and may be prepared by reacting a compound containing the piperazine or homopiperazine part of the molecular with a compound containing the other part of the molecule.