1332637-10-1

Basic information

• Product Name: methyl 3-iodo-4-((4-(methoxycarbonyl)phenoxy)methyl)benzoate
• Synonyms: methyl 3-iodo-4-((4-(methoxycarbonyl)phenoxy)methyl)benzoate
• CAS NO: 1332637-10-1
• Molecular Weight: 426.208
• Mol File: 1332637-10-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3-iodo-4-((4-(methoxycarbonyl)phenoxy)methyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-iodo-4-((4-(methoxycarbonyl)phenoxy)methyl)benzoate(1332637-10-1)
• EPA Substance Registry System: methyl 3-iodo-4-((4-(methoxycarbonyl)phenoxy)methyl)benzoate(1332637-10-1)

Safety Data

• Hazardous Substances Data: 1332637-10-1(Hazardous Substances Data)

Upstream product

• 99-76-3 methyl 4-hydroxylbenzoate 
• 229028-10-8 methyl 4-(bromomethyl)-3-iodo-benzoate 

Downstream Products

• 1332637-18-9 dimethyl 2-hydroxy-6'-(2-(tosyloxy)ethyl)biphenyl-3,3'-dicarboxylate 

Relevant articles and documents

Targeting the heat shock protein 90 dimer with dimeric inhibitors

The design, synthesis, and biological evaluation of conformationally constrained coumermycin A1 analogues are reported. Compounds were evaluated against both breast cancer (SKBr3 and MCF7) and prostate cancer (PC3 mm2, A549, and HT29) cell lines. Non-noviosylated coumermycin A1 analogues that manifest potent antiproliferative activity resulting from Hsp90 inhibition are provided, wherein replacement of the stereochemically complex noviose sugar with readily available piperidine rings resulted in ü100 fold increase in antiproliferative activities as compared to coumermycin A1, producing small molecule Hsp90 inhibitors that exhibit nanomolar activities.