1333240-17-7 Usage
Description
2-Chloro-4,5-diMethoxy-pyriMidine is an organic compound characterized by its chlorinated and methoxy-substituted pyrimidine structure. It is a versatile intermediate in the synthesis of various biologically active molecules and pharmaceuticals.
Uses
Used in Pharmaceutical Industry:
2-Chloro-4,5-diMethoxy-pyriMidine is used as a reactant for the preparation of aryl-substituted 4-hydroxypyridazin-3(2H)-ones and 5-hydroxypyrimidin-4(3H)-ones. These compounds serve as inhibitors of influenza A endonuclease, which is a key enzyme in the replication of the influenza virus. By inhibiting this enzyme, the synthesis of viral RNA is disrupted, potentially leading to the development of antiviral drugs to combat influenza A infections.
Check Digit Verification of cas no
The CAS Registry Mumber 1333240-17-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,3,3,2,4 and 0 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1333240-17:
(9*1)+(8*3)+(7*3)+(6*3)+(5*2)+(4*4)+(3*0)+(2*1)+(1*7)=107
107 % 10 = 7
So 1333240-17-7 is a valid CAS Registry Number.
1333240-17-7Relevant articles and documents
THERAPEUTIC HYDROXYPYRIDINONES, HYDROXYPYRIMIDINONES AND HYDROXYPYRIDAZINONES
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Page/Page column 64, (2014/04/03)
The invention provides compounds of formula (I): and salts and prodrugs thereof wherein R4, X1 and X2 have any of the meanings defined in the specification, as well as pharmaceutical compositions comprising the compounds or salts and methods for their use in therapy. The compounds have useful antiviral properties.
INHIBITORS OF CATECHOL O-METHYL TRANSFERASE AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS
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Page/Page column 46-47, (2011/10/03)
The present invention relates to 4-pyridinone compounds which are inhibitors of catechol O-methyltransferase (COMT), and are useful in the treatment and prevention of neurological and psychiatric disorders and diseases in which COMT enzyme is involved. The present invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which COMT is involved.