1333325-91-9Relevant articles and documents
Pd-and Cu-catalyzed stereo-and regiocontrolled decarboxylative/C-H fluoroalkenylation of heteroarenes
Rouse, Kevin,Schneider, Cdric,Couve-Bonnaire, Samuel,Pannecoucke, Xavier,Levacher, Vincent,Hoarau, Christophe
supporting information, p. 1500 - 1504 (2015/01/09)
Pd/Cu-catalyzed decarboxylative/direct C-H alkenylations of heteroarenes with α-fluoroacrylic acid is reported. This method offers step-economical and stereocontrolled access to valuable heteroarylated monofluoroalkenes as both Z and E isomers, which are known to be useful in the synthesis of fluorinated biomolecules.