1333478-77-5

Basic information

• Product Name: C₂₉H₂₁Cl₂N₃O
• CAS NO: 1333478-77-5
• Molecular Weight: 498.411
• Mol File: 1333478-77-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₉H₂₁Cl₂N₃O(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₉H₂₁Cl₂N₃O(1333478-77-5)
• EPA Substance Registry System: C₂₉H₂₁Cl₂N₃O(1333478-77-5)

Safety Data

• Hazardous Substances Data: 1333478-77-5(Hazardous Substances Data)

Upstream product

• 3453-33-6 6-methoxynaphthalene-2-carbaldehyde 
• 79560-19-3 4-(3,4-dichlorophenyl)-3,4-dihydro-2H-naphthalen-1-one 
• 1227614-52-9 C₂₈H₂₀Cl₂O₂ 
• 113-00-8 guanidine nitrate 

Relevant articles and documents

Synthesis of some amino-pyrimidines and pyrazolines as potent antimicrobial agents

Base catalysed condensation of ketone (1) with different aromatic aldehydes afforded chalcones (2E)-2-arylidene-4-(3,4-dichlorophenyl)-3,4- dihydronaphthalen-1(2H)-ones (2a-j). These chalcones on cyclization with guanidine hydrochloride in the presence of few drops of sodium hydroxide in abs alcohol resulted in the formation of 2-amino-4-aryl-6-(3,4-dichlorophenyl)-5,6- dihydrobenzo [h] pyrimidines (3a-j). The cyclocondensation of 2a-j with phenyl hydrazine in the presence of triethylamine in abs alcohol yielded 3-aryl-5-(3,4-dichlorophenyi)-2-phenyl-3. 3a, 4,5-tetrahydro-2H-benzo [g] pyrazolines (4a-j). The structures of new compounds have been established by spectroscopic and elemental analysis. The new compounds have been tested for their antimicrobial activity.