1333481-66-5Relevant articles and documents
Selective water-soluble gelatinase inhibitor prodrugs
Gooyit, Major,Lee, Mijoon,Schroeder, Valerie A.,Ikejiri, Masahiro,Suckow, Mark A.,Mobashery, Shahriar,Chang, Mayland
, p. 6676 - 6690 (2011/12/02)
SB-3CT (1), a selective and potent thiirane-based gelatinase inhibitor, is effective in animal models of cancer metastasis and stroke; however, it is limited by poor aqueous solubility and extensive metabolism. We addressed these issues by blocking the pr