133392-27-5Relevant articles and documents
Stereoselective Synthesis of Optically Active 2-Hydroxymandelic Acids and Esters via Friedel-Crafts Coordinated Reaction: Crystal Structure of Chiral Dichloro[2-(1-oxido-1-menthoxycarbonylmethyl)-4-methoxyphenoxido-O,O,O] titanium?
Bigi, Franca,Bocelli, Gabriele,Maggi, Raimondo,Sartori, Giovanni
, p. 5004 - 5009 (2007/10/03)
Highly diastereoselective hydroxyalkylation of phenols with chiral glyoxylates was performed. Hydrolysis or reduction of the esters 3 afforded 2-hydroxymandelic acids 6 and diols 5 in high yields and enantiomeric pure form. Mechanistic evidence of chelati