1334333-29-7

Basic information

• Product Name: methyl 4-(3,5-dimethylpyridin-2-yl)-2-methylene-3-phenylbutanoate
• Synonyms: methyl 4-(3,5-dimethylpyridin-2-yl)-2-methylene-3-phenylbutanoate
• CAS NO: 1334333-29-7
• Molecular Weight: 295.381
• Mol File: 1334333-29-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 4-(3,5-dimethylpyridin-2-yl)-2-methylene-3-phenylbutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(3,5-dimethylpyridin-2-yl)-2-methylene-3-phenylbutanoate(1334333-29-7)
• EPA Substance Registry System: methyl 4-(3,5-dimethylpyridin-2-yl)-2-methylene-3-phenylbutanoate(1334333-29-7)

Safety Data

• Hazardous Substances Data: 1334333-29-7(Hazardous Substances Data)

Upstream product

• 695-98-7 2,3,5-trimethyl-pyridine 
• 1352054-17-1 Br^(1-)*C₁₉H₂₂NO₂⁽¹⁺⁾ 
• 956833-12-8 methyl 2-{[(tert-butoxycarbonyl)oxy](phenyl)methyl}acrylate 

Relevant articles and documents

Direct C(sp3)–H allylation of 2-alkylpyridines with Morita–Baylis–Hillman carbonates via a tandem nucleophilic substitution/aza-Cope rearrangement

A base- and catalyst-free C(sp3)–H allylic alkylation of 2-alkylpyridines with Morita–Baylis–Hillman (MBH) carbonates is described. A plausible mechanism of the reaction might involve a tandem SN2’ type nucleophilic substitution followed by an aza-Cope rearrangement. Various alkyl substituents on 2-alkylpyridines were tolerated in the reaction to give the allylation products in 26–91% yields. The developed method provides a straightforward and operational simple strategy for the allylic functionalization of 2-alkypyridine derivatives.