1334390-84-9

Basic information

• Product Name: 6-(4-aminophenoxy)benzo[d]thiazole-2-carbonitrile
• Synonyms: 6-(4-aminophenoxy)benzo[d]thiazole-2-carbonitrile
• CAS NO: 1334390-84-9
• Molecular Weight: 267.311
• Mol File: 1334390-84-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-(4-aminophenoxy)benzo[d]thiazole-2-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(4-aminophenoxy)benzo[d]thiazole-2-carbonitrile(1334390-84-9)
• EPA Substance Registry System: 6-(4-aminophenoxy)benzo[d]thiazole-2-carbonitrile(1334390-84-9)

Safety Data

• Hazardous Substances Data: 1334390-84-9(Hazardous Substances Data)

Upstream product

• 350-46-9 4-Fluoronitrobenzene 
• 939-69-5 2-cyano-6-hydroxybenzothiazole 

Relevant articles and documents

Bioluminescent probe for detecting endogenous hypochlorite in living mice

As a kind of biologically important reactive oxygen species (ROS), hypochlorite (ClO-) plays a crucial role in many physiological processes. As such, endogenous ClO- is a powerful antibacterial agent during pathogen invasion. Nonetheless, excessive endogenous ClO- could pose a health threat to mammalian animals including humans. However, the detection of endogenous ClO- by bioluminescence probes in vivo remains a considerable challenge. Herein, based on a caged strategy, we developed a turn-on bioluminescent probe 1 for the highly selective detection of ClO-in vitro and imaging endogenous ClO- in a mouse inflammation model. We anticipate that such a probe could help us understand the role of endogenous ClO- in a variety of physiological and pathological processes.