133461-92-4

Basic information

• Product Name: PropanaMide, N-(2-acetylphenyl)-2-Methyl-
• Synonyms: PropanaMide, N-(2-acetylphenyl)-2-Methyl-
• CAS NO: 133461-92-4
• Molecular Formula: C₁₂H₁₅NO₂
• Molecular Weight: 205.253
• Mol File: 133461-92-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 379.5±25.0 °C(Predicted)
• Appearance: /
• Density: 1.095±0.06 g/cm3(Predicted)
• PKA: 14.31±0.70(Predicted)
• CAS DataBase Reference: PropanaMide, N-(2-acetylphenyl)-2-Methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: PropanaMide, N-(2-acetylphenyl)-2-Methyl-(133461-92-4)
• EPA Substance Registry System: PropanaMide, N-(2-acetylphenyl)-2-Methyl-(133461-92-4)

Safety Data

• Hazardous Substances Data: 133461-92-4(Hazardous Substances Data)

Upstream product

• 551-93-9 2-aminoacetophenone 
• 79-30-1 isobutyryl chloride 
• 97-72-3 2-Methylpropionic anhydride 

Relevant articles and documents

Selective Oxidative Decarbonylative Cleavage of Unstrained C(sp3)-C(sp2) Bond: Synthesis of Substituted Benzoxazinones

A transition metal (TM)-free practical synthesis of biologically relevant benzoxazinones has been established via a selective oxidative decarbonylative cleavage of an unstrained C(sp3)-C(sp2) bond employing iodine, sodium bicarbonate, and tbutyl hydroperoxide in DMSO at 95 °C. Control experiments and Density Functional Theory (DFT) calculations suggest that the reaction involves a [1,5]H shift and extrusion of CO gas as the key steps. The extrusion of CO has also been established using PMA-PdCl2.