133490-05-8

Basic information

• Product Name: Cyclohexene, 4-(1-isothiocyanato-1-methylethyl)-1-methyl-
• CAS NO: 133490-05-8
• Molecular Formula: C11H17NS
• Molecular Weight: 195.329
• Mol File: 133490-05-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Cyclohexene, 4-(1-isothiocyanato-1-methylethyl)-1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexene, 4-(1-isothiocyanato-1-methylethyl)-1-methyl-(133490-05-8)
• EPA Substance Registry System: Cyclohexene, 4-(1-isothiocyanato-1-methylethyl)-1-methyl-(133490-05-8)

Safety Data

• Hazardous Substances Data: 133490-05-8(Hazardous Substances Data)

Upstream product

• 39864-10-3 α-terpinyl chloride 
• 333-20-0 potassium thioacyanate 
• 557-42-6 zinc(II) thiocyanate 
• 5989-27-5 D-limonene 

Relevant articles and documents

Microwave-assisted synthesis of alkyl thiocyanates

Microwave irradiation accelerated the reaction of t-alkyl, allyl, and benzyl halides with Zn(SCN)2 to afford thiocyanates in excellent yields and high selectivity with the formation of isothiocyanates only in minor proportions. Because thiocyanates are stable intermediates to thiols, the method also affords facile access to corresponding thiols.

Simple synthetic protocols for tertiary alkyl and allyl thiols

Convenient preparative methods for tertiary alkyl and allyl thiols are described. Accordingly, thiolesters and thiocyanates, obtained from the reaction of SN1-active halides and appropriate zinc salts, on hydrolysis and LAH reduction respectively, afford the corresponding thiols in near quantitative yields. Besides the well known p-menth-1-ene-8-thiol, p-menthane-1-thiol, p-mentha-1,8-diene-6-thiol and 2-(2-phenyl)propane thiol have been prepared.