1335016-30-2

Basic information

• Product Name: C₂₄H₂₅N₇O₃S₂
• Synonyms: C₂₄H₂₅N₇O₃S₂
• CAS NO: 1335016-30-2
• Molecular Weight: 523.64
• Mol File: 1335016-30-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₄H₂₅N₇O₃S₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₂₅N₇O₃S₂(1335016-30-2)
• EPA Substance Registry System: C₂₄H₂₅N₇O₃S₂(1335016-30-2)

Safety Data

• Hazardous Substances Data: 1335016-30-2(Hazardous Substances Data)

Upstream product

• 6376-75-6 4-Ethoxycarbonylmethyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazine 
• 137-07-5 2-amino-benzenethiol 
• 100637-60-3 2-(3-oxo-2,3-dihydro-4H-benzo[b][1,4]thiazin-4-yl)acetic acid 
• 5325-20-2 2H-1,4-benzothiazin-3-one 
• 1335015-79-6 4-[(4-amino-5-sulfanyl-4H-1,2,4-triazol-3-yl)methyl]-2H-1,4-benzothiazin-3(4H)-one 
• 110-89-4 piperidine 
• 50-00-0 formaldehyd 
• 1335015-90-1 4-{[4-(p-nitro-benzylideneamino)-5-sulfanyl-1,2,4-triazol-3-yl]methyl}-2H-1,4-benzothiazin-3(4H)-one 

Relevant articles and documents

Synthesis, characterization and pharmacological activity of 4-{[1-substituted aminomethyl-4-arylideneamino-5-sulfanyl-4,5-dihydro-1H-1,2,4- triazol-3-yl]methyl}-2H-1,4-benzothiazin-3(4H)-ones

A new series of Schiff and Mannich bases derivatives (6) of 4-[(4-amino-5-sulfanyl-4H-1,2,4-triazol-3-yl)methyl]-2H-1,4-benzothiazin-3(4H) -one (4), derived from (3-oxo-2,3-dihydro-4H-1,4-benzothiazin-4-yl)acetic acid (3) were synthesized. The structures of all newly synthesized compounds were elucidated by elemental analysis, IR, 1H NMR and mass spectral data. Synthesized compounds were evaluated for their anti-inflammatory and analgesic activity. Among the tested compounds, the (3-oxo-2,3-dihydro-4H-1,4- benzothiazin-4-yl)acetic acid (3) possess analgesic activity comparable to that of pentazocine; activity decreased on derivatization of the carboxylic acid group. However the anti-inflammatory activity of (3-oxo-2,3-dihydro-4H-1,4- benzothiazin-4-yl)acetic acid (3) increased by derivatization of the carboxylic acid group and some of the compounds showed anti-inflammatory activity comparable to that of indomethacin.