1335114-88-9Relevant articles and documents
Synthesis of ortho-substituted nitroaromatics via improved Negishi coupling conditions
Tuttle, Jamison B.,Azzarelli, Joseph M.,Bechle, Bruce M.,Dounay, Amy B.,Evrard, Edelweiss,Gan, Xinmin,Ghosh, Somraj,Henderson, Jaclyn,Kim, Ji-Young,Parikh, Vinod D.,Verhoest, Patrick R.
experimental part, p. 5211 - 5213 (2011/10/12)
We describe modified Negishi coupling conditions that allow improved access to ortho-nitrophenylalanine derivatives. These useful amino acid intermediates can be further elaborated into biologically active lactams and cyclic hydroxamic acid targets.