1335230-80-2

Basic information

• Product Name: C₃₁H₂₇BrN₃OP
• Synonyms: C₃₁H₂₇BrN₃OP
• CAS NO: 1335230-80-2
• Molecular Weight: 568.453
• Mol File: 1335230-80-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₃₁H₂₇BrN₃OP(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₁H₂₇BrN₃OP(1335230-80-2)
• EPA Substance Registry System: C₃₁H₂₇BrN₃OP(1335230-80-2)

Safety Data

• Hazardous Substances Data: 1335230-80-2(Hazardous Substances Data)

Upstream product

• 1236163-12-4 N,N-naphthalen-1-ylmethyl phosphoramide 
• 1122-91-4 4-bromo-benzaldehyde 

Downstream Products

• 1236163-03-3 C₃₂H₂₈BrN₄OP 

Relevant articles and documents

STRECKER REAGENTS, THEIR DERIVATIVES, METHODS FOR FORMING THE SAME AND IMPROVED STRECKER REACTION

Strecker reagents, their derivatives and methods for forming the same and improved Strecker reaction are provided. The electrophiles for asymmetric Strecker reaction include achiral N-phosphorazides, N-phosphoramides, N-phosphonyl imines and their derivat

Asymmetric catalytic n -phosphonyl imine chemistry: The use of primary free amino acids and Et2AlCN for asymmetric catalytic strecker reaction

(Figure presented) The new asymmetric catalytic Strecker reaction of achiral N-phosphonyl imines has been established. Excellent enantioselectivity (95.2-99.7% ee) and yields (89-97%) have been achieved by using primary free natural amino acids as catalysts and Et2AlCN as nucleophile. This work also presents the novel use of nonvolatile and inexpensive Et 2AlCN in asymmetric catalysis. The N-phosphonyl protecting group enabled simple product purification to be achieved simply by washing the crude products with hexane, which is defined as the GAP chemistry (GAP: Group-Assistant-Purification).(17)It can also be readily cleaved and recycled under mild condition to give a quantitative recovery of N,N′- bis(naphthalen-1-ylmethyl)ethane-1,2-diamine. A new mechanism was proposed for this reaction and was supported by experimental observations.