133576-76-8 Usage
Description
(1R,2S)-N-Piperidinonorephedrine is a psychoactive chemical compound that functions as a noradrenaline reuptake inhibitor. It is structurally related to ephedrine and is derived from the combination of piperidine and the neurotransmitter norepinephrine. (1R,2S)-N-Piperidinonorephedrine is known for its ability to elevate norepinephrine levels in the brain, which can result in enhanced focus, increased energy, and reduced appetite. However, it also presents potential risks such as increased blood pressure, heart palpitations, and the possibility of addiction or dependence. Due to these concerns, (1R,2S)-N-Piperidinonorephedrine is subject to strict regulations and is not widely utilized in medical or recreational contexts.
Uses
Used in Pharmaceutical Research:
(1R,2S)-N-Piperidinonorephedrine is used as a research compound for studying the effects of noradrenaline reuptake inhibition on cognitive function, energy levels, and appetite regulation. Its psychoactive properties and the potential therapeutic benefits it may offer are of interest to scientists exploring new treatments for various conditions.
Used in Drug Development:
In the field of drug development, (1R,2S)-N-Piperidinonorephedrine serves as a lead compound for the creation of new medications that aim to harness its noradrenaline-increasing effects while minimizing the associated risks. This could potentially lead to the development of safer and more effective treatments for conditions that may benefit from increased norepinephrine levels.
Used in Regulatory and Safety Studies:
(1R,2S)-N-Piperidinonorephedrine is also used in regulatory and safety studies to understand the potential risks associated with its use, including the risk of addiction and dependence. These studies are crucial for establishing guidelines and regulations to ensure the safe use of this compound in any potential medical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 133576-76-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,5,7 and 6 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 133576-76:
(8*1)+(7*3)+(6*3)+(5*5)+(4*7)+(3*6)+(2*7)+(1*6)=138
138 % 10 = 8
So 133576-76-8 is a valid CAS Registry Number.
133576-76-8Relevant articles and documents
Preparation of [R-(R,S)]-?-methyl-?-phenyl-1-pyrrolidineethanol: [ 1-Pyrrolidineethanol, ?-methyl-?-phenyl-, [R-(R,S)]- ]
Zhao, Dalian,Chen, Cheng-yi,Xu, Feng,Tan, Lushi,Tillyer, Richard,Pierce, Michael E.,Moore, James R.,Burton, Jonathan W.,Holmes, Andrew B.
, p. 12 - 12 (2017/09/19)
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Chiral Arene Chromium Tricarbonyl Complexes as Enantioselective Catalysts: Highly Selective 1,2-Alkyl Additions to Aldehydes
Heaton, Steven B.,Jones, Graham B.
, p. 1693 - 1696 (2007/10/02)
The preparation of a rationally designed catalyst system derived from norephedrine is reported.The key stereodirective element emanates from a chromium tricarbonyl group complexed to one face of the aryl ring.The catalysts mediate the addition of diethyl zinc to a variety of aldehydes with extremely high enantioselectivity.Key Words: enantioselective catalyst; norephedrine; arene chromium tricarbonyl; diethyl zinc; chiral 1,2-addition
