13363-59-2

Basic information

• Product Name: 2,2'-Dithiobis(3-methylbenzoic acid)
• Synonyms: BENZOIC ACID, 2,2'-DITHIOBIS[3-METHYL]-;2,2'-dithiobis(3-methylbenzoic acid);Benzoic Acid,2,2'-Dithiobis[3-meethyl-;2,2'-Dithiobis[3-meethyl] Benzoic Acid
• CAS NO: 13363-59-2
• Molecular Formula: C₁₆H₁₄O₄S₂
• Molecular Weight: 334.41
• Mol File: 13363-59-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 251-253 °C
• Boiling Point: 490.148 °C at 760 mmHg
• Flash Point: 250.233 °C
• Appearance: /
• Density: 1.448 g/cm³
• PKA: 3.13±0.36(Predicted)
• CAS DataBase Reference: 2,2'-Dithiobis(3-methylbenzoic acid)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2'-Dithiobis(3-methylbenzoic acid)(13363-59-2)
• EPA Substance Registry System: 2,2'-Dithiobis(3-methylbenzoic acid)(13363-59-2)

Safety Data

• Hazardous Substances Data: 13363-59-2(Hazardous Substances Data)

Usage

General Description

2,2'-Dithiobis(3-methylbenzoic acid) is a chemical compound that belongs to the class of thiobenzoic acids. It is an organic compound with the molecular formula C16H14O4S2 and a molar mass of 334.41 g/mol. The compound is a white crystalline solid that is sparingly soluble in water but soluble in organic solvents. It is commonly used as a reagent in organic synthesis and is a building block for the preparation of various organic compounds and materials. It has applications in the pharmaceutical and chemical industries, as well as in academic research. 2,2'-Dithiobis(3-methylbenzoic acid) is known for its ability to form coordination complexes with metals, making it useful in catalytic processes and as a chelating agent.

Upstream product

• 24010-56-8 2,6-dimethylbenzenesulfonamide 
• 77149-11-2 3-methyl-2-mercaptobenzoic acid 
• 4389-45-1 3-methylantranilic acid 
• 80447-63-8 2-<(ethoxythioxomethyl)thio>-3-methylbenzoic acid 

Downstream Products

• 77149-11-2 3-methyl-2-mercaptobenzoic acid 
• 13363-60-5 2,2'-dithiobis<3-methylbenzoyl chloride> 

Relevant articles and documents

Thiol-dependent DNA cleavage by aminomethylated Beaucage's reagent

Aminomethylated Beaucage's reagent 1 was found to be more potent than 3H-1,2-benzodithiol-3-one 1,1-dioxide (Beaucage's reagent) in causing DNA cleavage. The current study demonstrated the importance of the amino functionality in enhancing DNA-cleaving ac

"Mercaptan-Tail" Porphyrins: Synthetic Analogues for the Active Site of Cytochrome P-450

The synthesis and characterization of a series of tetraarylporphyrins which bear covalently attached alkyl and aryl mercaptans designed to serve as axial ligands are described.The coordination chemistry of the iron(II) complexes of these "mercaptan-tail" porphyrins has been investigated by 1H NMR, IR, and electronic absorption spectroscopy, magnetic circular dichroism, and magnetic susceptibility measurements.Ferrous complexes of the alkyl mercaptan-tail porphyrins appear to remain four-coordinate, intermediate spin (S = 1) in solution.The situation is less clear in the case of appended aryl mercaptans and a "tail-on/tail-off" equilibrium is implicated.In the presence of carbon monoxide, however, binding of thiol trans to CO is observed in both the alkyl and aryl cases.By the addition of an appropriate base, six-coordinate mercaptide-Fe(II)-CO complexes can be generated; these reproduce quite well the characteristic absorption and MCD spectra of cytochrome P-450, suggesting that such compounds are indeed viable models for the active site of cytochrome P-450.

Preparation and antifungal activity of bz.methyl-substituted bis-(2-carboxyamidophenyl)disulfides and 1,2-benzoisothiazoline-3-ones

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