133658-45-4

Basic information

• Product Name: ANANTIN (LINEAR SEQUENCE)
• Synonyms: CYCLO[GLY-PHE-ILE-GLY-TRP-GLY-ASN-BETA-ASP]-ILE-PHE-GLY-HIS-TYR-SER-GLY-ASP-PHE;GLY-PHE-ILE-GLY-TRP-GLY-ASN-ASP-ILE-PHE-GLY-HIS-TYR-SER-GLY-ASP-PHE;H-GLY-PHE-ILE-GLY-TRP-GLY-ASN-ASP-ILE-PHE-GLY-HIS-TYR-SER-GLY-ASP-PHE-OH;ANANTIN;ANANTIN (LINEAR SEQUENCE);anantin from streptomyces coerulescens;Cyclo[L-Phe-L-Ile-Gly-L-Trp-Gly-L-Asn-L-βαAsp-(L-Ile-L-Phe-Gly-L-His-L-Tyr-L-Ser-Gly-L-Asp-L-Phe-OH)-Gly-];Cyclo[L-Phe-L-Ile-Gly-L-Trp-Gly-L-Asn-βαAsp-(L-Ile-L-Phe-Gly-L-His-L-Tyr-L-Ser-Gly-L-Asp-L-Phe-OH)-Gly-]
• CAS NO: 133658-45-4
• Molecular Formula: C90H111N21O24
• Molecular Weight: 1870.97
• Mol File: 133658-45-4.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: ANANTIN (LINEAR SEQUENCE)(CAS DataBase Reference)
• NIST Chemistry Reference: ANANTIN (LINEAR SEQUENCE)(133658-45-4)
• EPA Substance Registry System: ANANTIN (LINEAR SEQUENCE)(133658-45-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 133658-45-4(Hazardous Substances Data)

Usage

Description

ANANTIN (LINEAR SEQUENCE) is a novel linear peptide with potent broad-spectrum antibacterial activity against a variety of pathogenic bacteria, including antibiotic-resistant strains. It also exhibits promising antifungal and antiviral properties. ANANTIN works by disrupting the bacterial cell membrane, leading to cell death. It has a relatively low toxicity profile and is considered a potential candidate for the development of new antimicrobial drugs to combat antibiotic resistance.

Uses

Used in Pharmaceutical Industry:
ANANTIN (LINEAR SEQUENCE) is used as an antimicrobial agent for its broad-spectrum activity against pathogenic bacteria, including antibiotic-resistant strains. It is also being explored for its antifungal and antiviral properties.
Used in Combating Antibiotic Resistance:
ANANTIN (LINEAR SEQUENCE) is used as a potential candidate for the development of new antimicrobial drugs to address the growing issue of antibiotic resistance.
Used in Therapeutic Applications:
Due to its relatively low toxicity profile, ANANTIN (LINEAR SEQUENCE) is used as a promising option for therapeutic use in clinical settings. Further research and clinical trials are needed to fully understand its potential in these applications.

InChI:InChI=1/C90H111N21O24/c1-5-48(3)77-88(132)99-46-75(120)101-61(36-54-41-94-57-25-17-16-24-56(54)57)80(124)97-43-72(117)102-62(37-68(91)114)83(127)106-64(39-70(115)95-42-71(116)100-59(86(130)110-77)33-51-20-12-8-13-21-51)87(131)111-78(49(4)6-2)89(133)107-58(32-50-18-10-7-11-19-50)79(123)96-44-73(118)103-63(38-69-92-30-31-93-69)84(128)105-60(34-53-26-28-55(113)29-27-53)82(126)109-67(47-112)81(125)98-45-74(119)104-65(40-76(121)122)85(129)108-66(90(134)135)35-52-22-14-9-15-23-52/h7-31,41,48-49,58-67,77-78,94,112-113H,5-6,32-40,42-47H2,1-4H3,(H2,91,114)(H,92,93)(H,95,115)(H,96,123)(H,97,124)(H,98,125)(H,99,132)(H,100,116)(H,101,120)(H,102,117)(H,103,118)(H,104,119)(H,105,128)(H,106,127)(H,107,133)(H,108,129)(H,109,126)(H,110,130)(H,111,131)(H,121,122)(H,134,135)