1337538-58-5

Basic information

• Product Name: 6-((1r,4r)-4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxamido)hexanoic acid
• Synonyms: 6-((1r,4r)-4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxamido)hexanoic acid
• CAS NO: 1337538-58-5
• Molecular Weight: 350.415
• Mol File: 1337538-58-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-((1r,4r)-4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxamido)hexanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-((1r,4r)-4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxamido)hexanoic acid(1337538-58-5)
• EPA Substance Registry System: 6-((1r,4r)-4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxamido)hexanoic acid(1337538-58-5)

Safety Data

• Hazardous Substances Data: 1337538-58-5(Hazardous Substances Data)

Upstream product

• 71875-81-5 4-(N-maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester 
• 60-32-2 6-aminohexanoic acid 
• 1197-18-8 trans-4-aminomethyl-cyclohexyl-carboxylic acid 
• 69907-68-2 trans-4-([(2Z)-3-carboxyprop-2-enoyl]aminolmethyl)cyclohexanecarboxylic acid 

Downstream Products

• 1337538-59-6 C₂₂H₂₉N₃O₇ 

Relevant articles and documents

In situ formation of N-trifluoroacetoxy succinimide (TFA-NHS): One-pot formation of succinimidyl esters, N-trifluoroacetyl amino acid succinimidyl esters, and N-maleoyl amino acid succinimidyl esters

A method for the in situ formation of N-trifluoroacetoxy succinimide (TFA-NHS) and its application in the formation of succinimidyl esters is presented. The developed method provides N-trifluoroacetyl and N-maleoyl amino acid succinimidyl esters from a variety of amino acids using a one-pot, high-yielding protocol. Investigations into the formation of an N-maleoyl amino acid succinimidyl ester supported the proposal of a revised reaction mechanism, and contributed to the optimization of the reaction conditions.