1337567-54-0

Basic information

• Product Name: C₂₃H₂₁N₅O₆S₂
• CAS NO: 1337567-54-0
• Molecular Weight: 527.582
• Mol File: 1337567-54-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₁N₅O₆S₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₁N₅O₆S₂(1337567-54-0)
• EPA Substance Registry System: C₂₃H₂₁N₅O₆S₂(1337567-54-0)

Safety Data

• Hazardous Substances Data: 1337567-54-0(Hazardous Substances Data)

Upstream product

• 1337567-47-1 4-(5-amino-6-cyano-7-(3,4-dimethoxyphenyl)-7H-pyrano[2,3-d]thiazol-2-ylamino)benzenesulfonamide 
• 108-24-7 acetic anhydride 
• 14949-01-0 2-chloro-N-(4-sulfamoylphenyl)acetamide 
• 2972-80-7 3,4-dimethoxybenzylidenemalononitrile 
• 81059-98-5 2-(4-sulphonamidophenyl)-amino-Δ²-thiazolin-4-one 

Relevant articles and documents

Synthesis of some new thiazolopyrane and thiazolopyranopyrimidine derivatives bearing a sulfonamide moiety for evaluation as anticancer and radiosensitizing agents

A new series of thiazolopyrane 5a-d, 11-13 and thiazolopyranopyrimidine 6-10, 7b, 8b, and 14 derivatives bearing a sulfonamide moiety were designed and synthesized. The molecular design was performed using molecular operating environment software to predict the binding mode of the proposed compounds on hCAII. All the newly synthesized compounds were evaluated for their in vitro anticancer activity against human liver cancer cell line in which hCAII is overexpressed. Compounds 8b and 14 showed higher activities compared with doxorubicin as a positive control. The radiosensitizing ability of the promising compounds 3, 7a, 8b, 12, and 14 was studied which showed an increase in the cell killing effect of γ-radiation after combination with them. Springer Science+Business Media, LLC 2011.