133795-85-4Relevant articles and documents
Structure-Affinity Relationships of 2,3,4,5-Tetrahydro-1 H-3-benzazepine and 6,7,8,9-Tetrahydro-5 H-benzo[7]annulen-7-amine Analogues and the Discovery of a Radiofluorinated 2,3,4,5-Tetrahydro-1 H-3-benzazepine Congener for Imaging GluN2B Subunit-Containi
Ahmed, Hazem,Haider, Ahmed,Varisco, Jasmine,Stankovi?, Maja,Wallimann, Rahel,Gruber, Stefan,Iten, Irina,H?ne, Surya,Müller Herde, Adrienne,Keller, Claudia,Schibli, Roger,Schepmann, Dirk,Mu, Linjing,Wünsch, Bernhard,Ametamey, Simon M.
, p. 9450 - 9470 (2019/11/11)
Aspiring to develop a positron emission tomography (PET) imaging agent for the GluN2B subunits of the N-methyl-d-aspartate receptor (NMDAR), a key therapeutic target for drug development toward several neurological disorders, we synthesized a series of 2,
Binding of Substituted and Conformationally Restricted Derivatives of N-(3-Phenyl-n-propyl)-1-phenyl-2-aminopropane at ?-Receptors
Glennon, Richard A.,Ismaiel, Abd M.,Smith, J. Doyle,Yousif, Mamoun,El-Ashmawy, Mahmoud,et al.
, p. 1855 - 1859 (2007/10/02)
Certain benzomorphans, such as N-allylnormetazocine, are classical "?-opiates" that bind both at ? and phencyclidine (PCP) binding sites with modest affinity.Recently, we identified N-substituted 2-phenylaminoethane as being the primary ?-pharmacophore of
