133805-06-8

Basic information

• Product Name: <(R)-2-methyl-1,4-dioxaspiro<4.5>dec-2-yl>methyl p-toluenesulfonate
• Synonyms: <(R)-2-methyl-1,4-dioxaspiro<4.5>dec-2-yl>methyl p-toluenesulfonate
• CAS NO: 133805-06-8
• Molecular Weight: 340.441
• Mol File: 133805-06-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: <(R)-2-methyl-1,4-dioxaspiro<4.5>dec-2-yl>methyl p-toluenesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: <(R)-2-methyl-1,4-dioxaspiro<4.5>dec-2-yl>methyl p-toluenesulfonate(133805-06-8)
• EPA Substance Registry System: <(R)-2-methyl-1,4-dioxaspiro<4.5>dec-2-yl>methyl p-toluenesulfonate(133805-06-8)

Safety Data

• Hazardous Substances Data: 133805-06-8(Hazardous Substances Data)

Upstream product

• 133805-04-6 <(R,S)-2-methyl-1,4-dioxaspiro<4.5>dec-2-yl>methyl butyrate 
• 55117-03-8 (R,S)-2-methyl-1,4-dioxaspiro<4.5>decane-2-methanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 133868-49-2 (S)-2-methyl-1,4-dioxaspiro<4.5>decane-2-methanol 

Downstream Products

• 133868-47-0 (R)-2,3-dihydroxy-2-methylpropyl p-toluenesulfonate 

Relevant articles and documents

Preparation of dioxolane derivatives

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Facile Chemoenzymatic Preparation of Enantiomerically Pure 2-Methylglycerol Derivatives as Versatile Trifunctional C4-Synthons

Both enantiomers of a series of synthetically valuable 2-methylglycerol derivatives have been prepared with >99percent ee using a chemoenzymatic reaction sequence.The introduction of chirality was achieved by enantioselective esterification of 1,2-O-protected 2-methylglycerol 3 or enantioselective hydrolysis of its butyryl ester 4.The enzymatic reaction proceeded with unusually high selectivity and velocity for a primary alcohol (ester) substrate.