134-55-4 Usage
General Description
Phenyl O-acetylsalicylate, also known as acetylsalicylic acid phenyl ester, is a derivative of aspirin and belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). It is commonly used for its analgesic and antipyretic properties, as well as for its anti-inflammatory effects. The compound is synthesized by acetylating salicylic acid with phenol, resulting in a molecule that is less irritating to the stomach than traditional aspirin. Phenyl O-acetylsalicylate functions by inhibiting the production of prostaglandins, which are responsible for pain, fever, and inflammation. It is often used in pharmaceutical preparations for the relief of mild to moderate pain, such as headaches, muscle aches, and menstrual cramps. However, like other NSAIDs, it can have side effects such as gastrointestinal irritation, bleeding, and allergic reactions, and should be used cautiously and under the guidance of a healthcare professional.
Check Digit Verification of cas no
The CAS Registry Mumber 134-55-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,3 and 4 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 134-55:
(5*1)+(4*3)+(3*4)+(2*5)+(1*5)=44
44 % 10 = 4
So 134-55-4 is a valid CAS Registry Number.
InChI:InChI=1/C15H12O4/c1-11(16)18-14-10-6-5-9-13(14)15(17)19-12-7-3-2-4-8-12/h2-10H,1H3
134-55-4Relevant articles and documents
Cu(OTf)2-mediated Chan-Lam reaction of carboxylic acids to access phenolic esters
Zhang, Lingli,Zhang, Guoying,Zhang, Manli,Cheng, Jiang
experimental part, p. 7472 - 7474 (2011/01/03)
A Cu(OTf)2-mediated Chan-Lam reaction of carboxylic acids with arylboronic acids is described. It represents a facile and practical methodology to access phenolic esters in moderate to good yields. The procedure tolerates a series of functional groups, such as methoxycarbonyl, acetoxy, free phenolic hydroxyl, vinyl, nitro, trifluoromethyl, methoxyl, bromo, chloro, iodo, and acetyl groups.
Chemical feasibility studies concerning potential prodrugs of acetylsalicylic acid
Hansen,Senning
, p. 351 - 359 (2007/10/02)
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