1340595-19-8

Basic information

• Product Name: C₂₂H₂₀N₂
• Synonyms: C₂₂H₂₀N₂
• CAS NO: 1340595-19-8
• Molecular Weight: 312.414
• Mol File: 1340595-19-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₀N₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₀N₂(1340595-19-8)
• EPA Substance Registry System: C₂₂H₂₀N₂(1340595-19-8)

Safety Data

• Hazardous Substances Data: 1340595-19-8(Hazardous Substances Data)

Upstream product

• 886-66-8 1,4-diphenyl-1,3-butadiyne 
• 29239-89-2 4-ethyl-2-methyl-1⁽³⁾H-imidazole 

Relevant articles and documents

Hydro-amination/-amidation of 1,3-diynes with indoles/azoles/amides under modified Ullmann conditions: Stereo- and regio-selective synthesis of N-alkenynes via N-H bond activation

An efficient strategy for the stereo- and regio-selective synthesis of N-alkenynes has been described. The salient feature of the reaction involves hydro-amination/amidation of 1,3-diynes with indoles/azoles/ amides via transition-metal catalyzed activation of N-H bond. The resulting N-alkenynes derived from N-heterocycles and cyclic amides were obtained as a mixture of Z/E isomers with Z-stereoselectivity ranging from 60% to 95%. In contrast, acyclic amides afforded N-alkenynes with exclusive E-stereoselectivity, albeit in reduced yield ranging from ~10% to 41%.