134274-83-2

Basic information

• Product Name: naftifine
• Synonyms: naftifine
• CAS NO: 134274-83-2
• Molecular Weight: 287.404
• Mol File: 134274-83-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: naftifine(CAS DataBase Reference)
• NIST Chemistry Reference: naftifine(134274-83-2)
• EPA Substance Registry System: naftifine(134274-83-2)

Safety Data

• Hazardous Substances Data: 134274-83-2(Hazardous Substances Data)

Upstream product

• 104-54-1 3-Phenylpropenol 
• 14489-75-9 N-methyl-1-naphthalenemethylamine 
• 387383-30-4 N-(3-chloroallyl)-1-methyl-1-naphthylmethylamine 
• 100-58-3 phenylmagnesium bromide 

Relevant articles and documents

PH-Mediated Selective Synthesis of N-Allylic Alkylation or N-Alkylation Amines with Allylic Alcohols via an Iridium Catalyst in Water

Amination of allylic alcohols is an effective approach in the facile synthesis of N-allylic alkylation or N-alkylation amines. Recently, a series of catalysts were devised to push forward this transformation. However, current synthetic methods are typical

N-Methylcaprolactam as a Dipolar Aprotic Solvent for Iron-Catalyzed Cross-Coupling Reactions: Matching Efficiency with Safer Reaction Media

Although iron-catalysis provides a powerful alternative to the more conventional palladium and nickel in the cross-coupling arena, the major limitation is the necessity for carcinogenic N-methylpyrrolidone as a co-solvent in the vast majority of catalytic reactions. Herein, we introduce N-methylcaprolactam as an efficient, non-toxic and practical dipolar aprotic solvent for iron-catalyzed C(sp2)?C(sp3) alkylative cross-coupling of aryl chlorides and tosylates. The utility of this method is reflected by its wide substrate scope, high yields and capacity to cross-couple challenging alkyl organometallics prone to b-hydride elimination and homocoupling. Considering the broad utility of iron-catalyzed cross-coupling, we envision that N-methylcaprolactam will find wide application as a substitute for carcinogenic NMP.