1342843-72-4Relevant articles and documents
An efficient one-pot synthesis of pyrimido[2,1-b][1,3]thiazine derivatives by reaction of activated acetylenes, thiouracils, and isocyanides
Baharfar, Robabeh,Baghbanian, Seyed Meysam,Vahdat, Seyed Mohammad
, p. 6018 - 6020 (2011)
The reactive 1:1 zwitterionic intermediate, formed by the addition of isocyanides to dialkyl acetylenedicarboxylates, was trapped by thiouracils to yield a ketenimine intermediate, which cyclized and then rearranged to afford pyrimido[2,1-b][1,3]thiazines