134308-14-8 Usage
Description
(+)-CP 47,497 is a bicyclic cannabinoid (CB) analog known for its potent analgesic properties. It exhibits comparable or even superior efficacy to Δ9-tetrahydrocannabinol in various pharmacological effects, such as analgesia, motor depression, anticonvulsant activity, and hypothermia in mice, rats, and dogs. The dextrorotatory enantiomer of this compound, (+)-CP 47,497, demonstrates a strong affinity for the CB1 receptor (Ki = 4.15 nM).
Uses
Used in Pharmaceutical Industry:
(+)-CP 47,497 is used as a potent analgesic agent for its ability to alleviate pain effectively. It is particularly useful in the development of new medications targeting pain management, as it exhibits strong binding to the CB1 receptor, which plays a crucial role in the regulation of pain perception.
Used in Research and Development:
(+)-CP 47,497 serves as an important research tool in the study of cannabinoid receptors and their role in various physiological processes. Its potent analgesic activity and strong affinity for the CB1 receptor make it a valuable compound for investigating the therapeutic potential of cannabinoids in treating pain and other related conditions.
Used in Synthetic Cannabinoids:
(+)-CP 47,497 is utilized in the development and synthesis of novel cannabinoid-based compounds with potential applications in various medical and therapeutic areas. Its potent analgesic properties and interaction with the CB1 receptor make it a promising candidate for the creation of new synthetic cannabinoids with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 134308-14-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,3,0 and 8 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 134308-14:
(8*1)+(7*3)+(6*4)+(5*3)+(4*0)+(3*8)+(2*1)+(1*4)=98
98 % 10 = 8
So 134308-14-8 is a valid CAS Registry Number.
134308-14-8Relevant articles and documents
3-[2-Hydroxy-4-(substituted)phenyl]-cycloalkanol analgesic agents
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, (2008/06/13)
Cycloalkanones, cycloalkanols and unsaturated analogs thereof, each of which has at the 3-position a 2-hydroxy-4-substituted phenyl group wherein the 4-position substituent is alkyl which can have an oxygen atom as part of the chain, or aralkyl which can have an oxygen atom as part of the alkyl chain, their use for pharmacological and medicinal purposes, intermediates therefor and processes for their preparation.
